Results 101 to 110 of about 6,639,663 (358)

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Risks and Risk Management in Agriculture

open access: yesZeszyty Naukowe SGGW w Warszawie - Problemy Rolnictwa Światowego, 2013
Agriculture has always been exposed to a wide spectrum of risks. But it is largely undisputed that farmers have faced growing risks in recent years. More volatile agricultural and input prices, climate change, ongoing discussions about the future of the Common Agricultural Policy, increasing difficulty in finding qualified farm workers, and growing ...
Theuvsen, Ludwig, Theuvsen, Ludwig
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

New pathogenic mutation in LMNA gene: Clinical case of familial cardiomyopathy

open access: yesТерапевтический архив
We present a clinical case of familial LMNA-associated cardiomyopathy, confirmed by whole genome sequencing. The typical for lamin-associated cardiomyopathy indicates pathogenic nature of the mutation in the first exon of LMNA gene, previously considered
Svetlana Y. Kashtanova   +16 more
doaj   +1 more source

Energy Security Risks and Risks Mitigation: an Overview [PDF]

open access: yes
Central to the goals of competitiveness and sustainable development is the issue of energy. Is there enough? Where will it come from? What will it costs? Is its production and use environmentally sustainable?
George Kowalski, Sead Vilogorac
core  

The Global Risks Report 2016, 11th Edition [PDF]

open access: yes, 2016
Now in its 11th edition, The Global Risks Report 2016 draws attention to ways that global risks could evolve and interact in the next decade. The year 2016 marks a forceful departure from past findings, as the risks about which the Report has been ...

core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

GSE Risks [PDF]

open access: yes
This article was originally presented as a speech to the St. Louis Society of Financial Analysts, St.
William Poole
core  

Sovereign Risk and Bank Risk-Taking [PDF]

open access: yesSSRN Electronic Journal, 2016
In European countries recently hit by a sovereign debt crisis, banks have sharply raised their holdings of domestic sovereign debt, reduced credit to forms, and faced rising financing costs, raising concerns about economic and financial resilience. This paper develops a general equilibrium model with optimizing banks and depositors to account for these
openaire   +9 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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