Results 21 to 30 of about 904,575 (302)

p53 Reactivation by the small molecule RITA: molecular mechanisms [PDF]

, 2011
Inactivation of the tumor suppressor p53 is essential for the development and maintenance of cancer cells. Therefore, reactivation of p53 appears to be a promising strategy for anti-cancer therapy. We have previously identified the small molecule RITA
Grinkevich, Vera
core   +4 more sources

Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

Neoplasia: An International Journal for Oncology Research, 2017
Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling.
Armin Wiegering, Niels Matthes, Bettina Mühling, Monika Koospal, Anne Quenzer, Stephanie Peter, Christoph-Thomas Germer, Michael Linnebacher, Christoph Otto   +8 more
doaj   +1 more source

Tumor de células de Leydig: relato de três casos

Revista Brasileira de Cancerologia, 2022
Tumores das células de Leydig são as neoplasias mais comuns do estroma gonadal. Eles representam 3% dos tumores testiculares, porém apenas 10% dos casos apresentam comportamento maligno.
Giovane Pioner, Míriam Dambros, Douglas Bohnenberger, Jair Kolling, Fabiano Ligório, Dante Sicca, Carlos Ary Vargas Souto   +6 more
doaj   +1 more source

What Is the Best Proximal Anastomosis for the Free Right Internal Thoracic Artery during Bilateral Internal Thoracic Artery Revascularization? A Prospective, Randomized Study

Cardiology Research and Practice, 2014
Objective. Bilateral internal thoracic artery (BITA) grafting provides improved graft patency and potential survival advantage in selected patients as compared to single left internal thoracic artery (LITA) revascularization.
S. Neragi-Miandoab, R. E. Michler, F. Lalezarzadeh, R. Bello, J. J. DeRose   +4 more
doaj   +1 more source

Study on Therapeutic Action and Mechanism of TMZ Combined with RITA Against Glioblastoma

Cellular Physiology and Biochemistry, 2018
Background/Aims: Glioblastoma multiforme (GBM) is a malignant and aggressive central nervous system (CNS) tumor with high mortality and low survival rate. Effective treatment of GMB is a challenge worldwide. Temozolomide (TMZ) is a drug used to treat GBM,
Qinghua Wu, Zhongxu Cao, Weiwei Xiao, Li Zhu, Qian Xie, Ling Li, Bao  Zhang, Wei Zhao   +7 more
doaj   +1 more source

Radial Artery Versus Right Internal Thoracic Artery Versus Saphenous Vein as the Second Conduit for Coronary Artery Bypass Surgery: A Network Meta‐Analysis of Clinical Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background There remains uncertainty regarding the second‐best conduit after the internal thoracic artery in coronary artery bypass grafting. Few studies directly compared the clinical results of the radial artery (RA), right internal thoracic artery ...
Mario Gaudino, Roberto Lorusso, Mohamed Rahouma, Ahmed Abouarab, Derrick Y. Tam, Cristiano Spadaccio, Gaëlle Saint‐Hilary, Jeremy Leonard, Mario Iannaccone, Fabrizio D'Ascenzo, Antonino Di Franco, Giovanni Soletti, Mohamed K. Kamel, Christopher Lau, Leonard N. Girardi, Thomas A. Schwann, Umberto Benedetto, David P. Taggart, Stephen E. Fremes   +18 more
doaj   +1 more source

Differential diagnosis of unipolar versus bipolar depression by GSK3 levels in peripheral blood: a pilot experimental study

International Journal of Bipolar Disorders, 2023
Background The differential diagnosis of patients presenting for the first time with a depressive episode into unipolar disorder versus bipolar disorder is crucial to establish the correct pharmacological therapy (antidepressants vs mood stabilizers ...
Gianluca Rosso, Giuseppe Maina, Elena Teobaldi, Ilaria Balbo, Gabriele Di Salvo, Francesca Montarolo, Nicola Rizzo Pesci, Filippo Tempia, Eriola Hoxha   +8 more
doaj   +1 more source

Efectos antioxidantes de Moringa oleifera LAM en vitroplantas de banano clon Williams enraizadas en sistemas de inmersión temporal RITA

Agroecosistemas, 2020
La producción bananera es la segunda actividad económica de El Oro, pero con plantaciones de 40 años de edad que requieren renovar sistemas tradicionales con plantas jóvenes vigorosas. La micropropagación, como alternativa para obtener plantas de banano,
Franklin Miguel Ordoñez Castillo, María de los Ángeles Bernal Pita Da Veig , Nieves Pilar Vidal Gonzalez , Alexander Moreno Herrera   +3 more
doaj  

Sybil Unrest by Larissa Lai and Rita Wong [PDF]

, 2015
Review of Sybil Unrest by Larissa Lai and Rita ...
McGiffin, Emily
core   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source