Results 81 to 90 of about 904,575 (302)

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis   +11 more
wiley   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi   +10 more
wiley   +1 more source

Higher complement C4 gene copy number constitutes a shared genetic risk factor for giant cell arteritis and IgA vasculitis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +296 more
wiley   +1 more source

How wildlife respond to tropical cyclones: short‐term tactics and long‐term impacts

open access: yesBiological Reviews, EarlyView.
ABSTRACT From butterflies to lizards and from sharks to seabirds, wildlife exhibit tactics to survive the impacts of tropical cyclones, also known as hurricanes, cyclones, or typhoons depending on where they occur. Some species seek refuge during the storm by moving, some remain in place and ride it out, and others move longer distances, avoiding the ...
Erin L. Koen   +15 more
wiley   +1 more source

Fascia‐Fat‐Fascia “Sandwich Graft” Decreases Postoperative Cerebrospinal Fluid Leak Rate for High‐Flow Skull Base Defects

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Vidit M. Talati   +11 more
wiley   +1 more source

Independent Female Directors and Green Innovation in China: The Moderating Roles of Ownership Structure and Market Competition

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines the impact of independent female directors (IFDs) on green innovation (GI) among Chinese‐listed firms from 2008 to 2023. Additionally, we investigate the moderating effects of ownership structure and market competition on the relationship between IFD and GI.
Muhammad Usman   +4 more
wiley   +1 more source

Recombination alters the receptor binding and furin cleavage site in novel bat-borne HKU5-CoV-2 coronavirus

open access: yesMicrobiology Spectrum
HKU5-CoV-2 is a new bat-infecting coronavirus phylogenetically related to MERS-CoV. It has recently been confirmed that HKU5-CoV-2 can enter human cells and organoids in vitro via the ACE2 receptor, raising concerns about its pandemic potential due to ...
Ting-Yu Yeh   +9 more
doaj   +1 more source

Sekuliarumo fenomeno filosofiniai išsišakojimai

open access: yesProblemos, 2014
Knygos recenzija. Sekuliarizacija ir dabarties kultūra: kolektyvinė monografija / sud. Rita Šerpytytė. Autoriai: Rita Šerpytytė, Danutė Bacevičiūtė, Mintautas Gutauskas, Tomas Sodeika, Kristupas Sabolius, Vaiva Daraškevičiūtė, Sigita Maslauskaitė, Aušra ...
Jūratė Baranova
doaj   +1 more source

Green Ambiguity Shapes Sustainable Investing

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Green Exchange‐Traded Funds (ETFs) have experienced strong growth in recent years, reflecting increasing investor attention toward sustainability. However, these funds rely on a wide range of environmental metrics that are often weakly aligned, raising concerns about the meaning of greenness in sustainable investing.
Rita Laura D'Ecclesia   +2 more
wiley   +1 more source

Polyunsaturated fatty-acids diet increases fear discrimination in rats and IGF-2 receptors signaling in the auditory cortex

open access: yesScientific Reports
Recent studies suggest that diet influences brain functions, though its effects on emotional processes remain unclear. Here we explored how two high-fat diets affect innate and learned fear behaviors in rats.
Giulia Concina   +7 more
doaj   +1 more source

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