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Immunotherapy, 2017
Pemphigus is a severe autoimmune blistering disease mediated by pathogenic anti-desmoglein antibodies leading to an inter keratinocyte disjunction. Rituximab is a monoclonal antibody that binds to the CD-20 antigen of B lymphocytes, which causes B-cell depletion and a subsequent reduction in pathogenic autoantibodies.
Hebert, Vivien, Joly, Pascal
openaire +2 more sources
Pemphigus is a severe autoimmune blistering disease mediated by pathogenic anti-desmoglein antibodies leading to an inter keratinocyte disjunction. Rituximab is a monoclonal antibody that binds to the CD-20 antigen of B lymphocytes, which causes B-cell depletion and a subsequent reduction in pathogenic autoantibodies.
Hebert, Vivien, Joly, Pascal
openaire +2 more sources
BioDrugs, 2007
An important role for B cells in the immunopathogenesis of rheumatoid arthritis (RA) is recognized. Rituximab is a chimeric murine/human anti-CD20 monoclonal antibody that transiently depletes CD20+ B cells. A single course of rituximab (two intravenous infusions of 1,000mg given two weeks apart) with a stable dose of methotrexate significantly ...
James E, Frampton, Lesley J, Scott
openaire +2 more sources
An important role for B cells in the immunopathogenesis of rheumatoid arthritis (RA) is recognized. Rituximab is a chimeric murine/human anti-CD20 monoclonal antibody that transiently depletes CD20+ B cells. A single course of rituximab (two intravenous infusions of 1,000mg given two weeks apart) with a stable dose of methotrexate significantly ...
James E, Frampton, Lesley J, Scott
openaire +2 more sources
Rotten Rituximab: Rituximab Related ILD
B36. THE GOOD, THE BAD, AND THE UGLY: DRUG TOXICITY CASE REPORTS, 2023B.S.K.R. Sabbula, V. Mehta, J. Akella
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