Results 1 to 10 of about 15,079 (253)

Case report: Successful treatment of refractory membranous nephropathy with telitacicept

Frontiers in Immunology, 2023
Despite various treatment methods, the remission rate of membranous nephropathy remains limited. Refractory membranous nephropathy especially lacks effective treatment plans. Telitacicept achieves comprehensive inhibition of CD20-positive B cells, plasma
Lei Zhang, Hua Jin, Dong Wang, Yiping Wang   +3 more
exaly   +3 more sources

The role of TOMM20 in Mediating TERT translocation to mitochondria and its impact on mitophagy in membranous nephropathy [PDF]

BMC Nephrology
Background In idiopathic membranous nephropathy (MN)—now a leading glomerular cause of end-stage kidney disease—mitochondrial quality control via mitophagy is increasingly recognized as a determinant of podocyte fate, yet the molecular switches governing
Limiao Yang, Hongle Yang, Mingming Zhang, Feifei Zhang, Xiaomei Liu, Zhiping Zhang, Jing Wang, Xiaolu Chen, Yuexuan Wang, Rui Zhang, Weihao Li   +10 more
doaj   +2 more sources

Obinutuzumab after anti-rituximab antibody-associated treatment failure in membranous nephropathy: a case report [PDF]

Frontiers in Immunology
Rituximab is an established therapy for primary membranous nephropathy, but anti−rituximab antibodies (ARA) have been associated with rituximab treatment failure.
Jianying Guo, Anni Zhong, Di Wu, Yang Liu, Yuna Chen, Yi Xu, Ricong Xu, Qijun Wan   +7 more
doaj   +2 more sources

Primary Membranous Nephropathy With Enhanced Staining of Exostosin 1/Exostosin 2 in the Glomeruli: A Report of 2 Cases

Kidney Medicine, 2021
Technological advances have allowed the discovery of 6 subtypes of membranous nephropathy based on target antigens: M-type phospholipase A2 receptor (PLA2R), thrombospondin type 1 domain-containing 7A (THSD7A), neural epidermal growth factor-like 1 ...
Takamasa Iwakura, Chiemi Ema, Taichi Sato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Akihiko Kato, Hideo Yasuda   +7 more
doaj   +1 more source

The Efficacy of Rituximab in the Treatment of Membranous Nephropathy

Journal of Nepal Health Research Council, 2021
Rituximab is a chimeric monoclonal antibody directed against the CD20 expressed on B cells, originally used to treat lymphoma but is increasingly used for the treatment of autoimmune diseases.
Ruby Maharjan, Jin Wen Wang, Indra Kumar Shrestha   +2 more
doaj   +1 more source

The value of repeat kidney biopsy during an atypical course of membranous nephropathy

BMC Nephrology, 2022
Background The clinical trajectory for patients with primary membranous nephropathy ranges widely from spontaneous remission to a rapid decline in kidney function.
Sumaiya Ahmed, David Massicotte-Azarniouch, Mark Canney, Clare Booth, Paula Blanco, Gregory L. Hundemer   +5 more
doaj   +1 more source

Phospholipase A2 receptor (PLA2R) related membranous nephropathy - not specific for idiopathic cases any more [PDF]

Journal of Nephropathology, 2018
Context: Membranous nephropathy is among the most common causes of nephrotic syndrome in adults. Evidence Acquisitions: PubMed, EBSCO, Web of Science, directory of open access journals (DOAJ), EMBASE, and Google Scholar with keywords of phospholipase A2 ...
Bahar Bastani
doaj   +1 more source

Rapid diagnosis of membranous nephropathy based on serum and urine Raman spectroscopy combined with deep learning methods

Scientific Reports, 2023
Membranous nephropathy is the main cause of nephrotic syndrome, which has an insidious onset and may progress to end-stage renal disease with a high mortality rate, such as renal failure and uremia.
Xueqin Zhang, Xue Song, Wenjing Li, Cheng Chen, Miriban Wusiman, Li Zhang, Jiahui Zhang, Jinyu Lu, Chen Lu, Xiaoyi Lv   +9 more
doaj   +1 more source

Post-Transplant Thrombotic Microangiopathy due to a Pathogenic Mutation in Complement Factor I in a Patient With Membranous Nephropathy: Case Report and Review of Literature

Frontiers in Immunology, 2022
Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia and organ injury occurring due to endothelial cell damage and microthrombi formation in small vessels.
Maryam Saleem, Sana Shaikh, Zheng Hu, Nicola Pozzi, Anuja Java   +4 more
doaj   +1 more source

Clinicopathological features in membranous nephropathy with cancer: A retrospective single-center study and literature review

The International Journal of Biological Markers, 2019
Background: Membranous nephropathy is the most common glomerular disease related to malignancy. However, it is difficult to distinguish between true malignancy-related membranous nephropathy and idiopathic membranous nephropathy coincident with cancer ...
Dan Zhang, Chong Zhang, Fan Bian, Wenzhu Zhang, Gengru Jiang, Jun Zou   +5 more
doaj   +1 more source