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Membranous nephropathy [PDF]

Brazilian Journal of Nephrology, 2023
Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte, and has consequences on the glomerular basement membrane. It is more common in adults, especially over 50 years of age.
Márcio Dantas, Lázaro Bruno Borges Silva, Barbhara Thaís Maciel Pontes, Marlene Antônia dos Reis, Patrícia Soares Nunes de Lima, Miguel Moysés Neto   +5 more
doaj   +6 more sources

Rituximab in Membranous Nephropathy [PDF]

Kidney International Reports, 2021
Membranous nephropathy (MN) is the most common cause of primary nephrotic syndrome among adults. The identification of phospholipase A2 receptor (PLA2R) as target antigen in most patients changed the management of MN dramatically, and provided a rationale for B-cell depleting agents such as rituximab. The efficacy of rituximab in inducing remission has
Philipp Gauckler, Jae Il Shin, Federico Alberici, Vincent Audard, Annette Bruchfeld, Martin Busch, Chee Kay Cheung, Matija Crnogorac, Elisa Delbarba, Kathrin Eller, Stanislas Faguer, Kresimir Galesic, Siân Griffin, Martijn W.F. van den Hoogen, Zdenka Hrušková, Anushya Jeyabalan, Alexandre Karras, Catherine King, Harbir Singh Kohli, Gert Mayer, Rutger Maas, Masahiro Muto, Sergey Moiseev, Balazs Odler, Ruth J. Pepper, Luis F. Quintana, Jai Radhakrishnan, Raja Ramachandran, Alan D. Salama, Ulf Schönermarck, Mårten Segelmark, Lee Smith, Vladimír Tesař, Jack Wetzels, Lisa Willcocks, Martin Windpessl, Ladan Zand, Reza Zonozi, Andreas Kronbichler, Philipp Gauckler, Jae Il Shin, Federico Alberici, Vincent Audard, Annette Bruchfeld, Martin Busch, Chee Kay Cheung, Matija Crnogorac, Elisa Delbarba, Kathrin Eller, Stanislas Faguer, Kresimir Galesic, Siân Griffin, Martijn W.F. van den Hoogen, Zdenka Hrušková, Anushya Jeyabalan, Alexandre Karras, Catherine King, Harbir Singh Kohli, Gert Mayer, Rutger Maas, Masahiro Muto, Sergey Moiseev, Balazs Odler, Ruth J. Pepper, Luis F. Quintana, Jai Radhakrishnan, Raja Ramachandran, Alan D. Salama, Ulf Schönermarck, Mårten Segelmark, Lee Smith, Vladimír Tesař, Jack Wetzels, Lisa Willcocks, Martin Windpessl, Ladan Zand, Reza Zonozi, Andreas Kronbichler   +77 more
core   +14 more sources

The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]

Journal of Nephropharmacology
Membranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar, Leila Alem, Azadeh Khayyat, Mohammad Ali Esmaeil Pour   +3 more
doaj   +3 more sources

Case report: Successful treatment of refractory membranous nephropathy with telitacicept

Frontiers in Immunology, 2023
Despite various treatment methods, the remission rate of membranous nephropathy remains limited. Refractory membranous nephropathy especially lacks effective treatment plans. Telitacicept achieves comprehensive inhibition of CD20-positive B cells, plasma
Lei Zhang, Hua Jin, Dong Wang, Yiping Wang   +3 more
doaj   +3 more sources

Designing Clinical Trials for the Treatment of Membranous Nephropathy in the Anti-Phospholipase A2 Receptor 1 Era: Results of a NephCure Membranous Nephropathy Workshop

Glomerular Diseases
Primary membranous nephropathy is a common cause of adult-onset nephrotic syndrome, with an overall incidence of 12 cases per million per year.
Marco Prunotto, Patrick H. Nachman, Barbara S. Gillespie, Laurence H. Beck, Aliza M. Thompson, Austin H. Hu, Elizabeth A. Stafford, Josh M. Tarnoff, Brad H. Rovin   +8 more
doaj   +2 more sources

Phospholipase A2 receptor (PLA2R) related membranous nephropathy - not specific for idiopathic cases any more [PDF]

Journal of Nephropathology, 2018
Context: Membranous nephropathy is among the most common causes of nephrotic syndrome in adults. Evidence Acquisitions: PubMed, EBSCO, Web of Science, directory of open access journals (DOAJ), EMBASE, and Google Scholar with keywords of phospholipase A2 ...
Bahar Bastani
doaj   +3 more sources

Current research status of PLA2R and malignancy associated membranous nephropathy

Linchuang shenzangbing zazhi, 2021
As a common cause of nephropathy syndrome in adults, membranous nephropathy（MN）often leads to end-stage renal disease.PLA2R related testing may aid a definite diagnosis of idiopathic MN.In recent years, we have detected some patients of malignancy ...
Zhu Wan-ting, Wang Yan-qiu
doaj   +1 more source

Advances in the pathogenesis and clinical applications of PLA2R-associated membranous nephropathy

Linchuang shenzangbing zazhi
Membranous nephropathy is one of the main pathological types of nephrotic syndrome. PLA2R（phospholipase A2 receptor）associated membranous nephropathy is the predominant type of primary membranous nephropathy， also known as idiopathic membranous ...
Sun Miao-xin, Wang Ding-ding, Wu Hao-wen, Li Yun-xia, Cai Pan-pan, Xin Ye, Chai Wen-xiu, Zhao Xin-cheng, Li Zi-wei, Duan Li-ping   +9 more
doaj   +2 more sources

Membranous Nephropathy and Pulmonary Tuberculosis: An Uncommon Combination: Case Report [PDF]

European Medical Journal
It is imperative to evaluate for secondary causes of membranous glomerulonephritis, from infections such as hepatitis B and C, viruses and parasites, autoimmune diseases like systemic lupus erythematosus, and other neoplasms.
Puneet Bhuwania, Aniket Mule, Sanggita Checker   +2 more
doaj   +2 more sources

Evolution of chronic glomerular disease spectrum and epidemiological characteristics of membranous nephropathy

Linchuang shenzangbing zazhi, 2019
Objective To investigate the composition of chronic glomerular disease spectrum as well as the epidemiological characteristics of membranous nephropathy in Guangdong Provincial People’s Hospital in recent 18 years.
XIE Zhi-yong, LI Zhi-lian, DONG Wei, CHEN Yuan-han, TAO Yi-ming, LI Rui-zhao, WU Yan-hua, LIANG Hua-ban, FU Lei, SHI Wei, LIANG Xin-ling   +10 more
doaj   +1 more source