Results 31 to 40 of about 15,079 (253)

Recent progress in the pathogenesis of membranous nephropathy

Linchuang shenzangbing zazhi, 2022
Membranous nephropathy （MN） is a kind of autoimmune disease caused by forming immune complex of antigen and antibody in glomerulus.A definite diagnosis is dependent upon renal biopsy and serological PLA2R1 test.And serological test is vital for further ...
He Zhi-hua, Wang Li-hua
doaj  

Membranous Nephropathy in the Dog [PDF]

Veterinary Pathology, 1986
Membranous nephropathy, a disease syndrome characterized by severe proteinuria and often accompanied by the nephrotic syndrome, was identified in 29% of a population of 46 proteinuric dogs. Renal lesions were characterized by the presence of subepithelial immunoglobulin deposits distributed diffusely along the glomerular capillary wall. Advanced stages
R S, Jaenke, T A, Allen
openaire   +2 more sources

Contactin-1-Associated Membranous Nephropathy after Multiple mRNA 1273 COVID-19 Vaccinations: A Case Report

Glomerular Diseases
Contactin-1-associated membranous nephropathy is a rare type of membranous nephropathy typically seen in the setting of chronic inflammatory demyelinating polyneuropathy.
Jonathan E. Zuckerman, Anthony Sisk, Elliot Parham Copen, Stephen Copen   +3 more
doaj   +1 more source

Membranous Nephropathy with Crescents [PDF]

Journal of the American Society of Nephrology, 2011
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary to systemic lupus erythematosus, chronic infection, or drugs. Rapid decline in renal function in patients with membranous nephropathy may be due to renal vein thrombosis, malignant hypertension, or an additional superimposed destructive process ...
Amanda Walton, Basford, Julia, Lewis, Jamie P, Dwyer, Agnes B, Fogo   +3 more
openaire   +2 more sources

Designing Clinical Trials for the Treatment of Membranous Nephropathy in the Anti-Phospholipase A2 Receptor 1 Era: Results of a NephCure Membranous Nephropathy Workshop

Glomerular Diseases
Primary membranous nephropathy is a common cause of adult-onset nephrotic syndrome, with an overall incidence of 12 cases per million per year.
Marco Prunotto, Patrick H. Nachman, Barbara S. Gillespie, Laurence H. Beck, Aliza M. Thompson, Austin H. Hu, Elizabeth A. Stafford, Josh M. Tarnoff, Brad H. Rovin   +8 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Current research status of PLA2R and malignancy associated membranous nephropathy

Linchuang shenzangbing zazhi, 2021
As a common cause of nephropathy syndrome in adults, membranous nephropathy（MN）often leads to end-stage renal disease.PLA2R related testing may aid a definite diagnosis of idiopathic MN.In recent years, we have detected some patients of malignancy ...
Zhu Wan-ting, Wang Yan-qiu
doaj  

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy

Frontiers in Immunology, 2018
Membranous nephropathy is an immune kidney disease caused by IgG antibodies that form glomerular subepithelial immune complexes. Proteinuria is mediated by complement activation, as a result of podocyte injury by C5b-9, but the role of specific ...
Wentian Luo, Wentian Luo, Florina Olaru, Florina Olaru, Jeffrey H. Miner, Laurence H. Beck, Johan van der Vlag, Joshua M. Thurman, Dorin-Bogdan Borza, Dorin-Bogdan Borza   +9 more
doaj   +1 more source

Case Report: Membranous Nephropathy Secondary to Cobalamin C Disease

Frontiers in Medicine, 2022
BackgroundMutation of MMACHC causes inherited cobalamin C disease with methylmalonic academia (MMA) and homocysteinemia. Renal complications may also be present in patients with this deficiency.
Qiang Wang, Qi Wang, Yanxia Gao, Chenquan Tang, Zhaoli Gao, Zhao Hu   +5 more
doaj   +1 more source