Identification and Characterization of New Proteins in Podocyte Dysfunction of Membranous Nephropathy by Proteomic Analysis of Renal Biopsy [PDF]
, 2013 Interstitial fluid, obtained by gentle centrifugation of the renal biopsy specimen, is highly enriched in elements directly secreted by the kidney tissue and is suitable for proteomic analysis.
CAPPELLI, Gianni +7 more
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The International Journal of Biological Markers, 2019 Background: Membranous nephropathy is the most common glomerular disease related to malignancy. However, it is difficult to distinguish between true malignancy-related membranous nephropathy and idiopathic membranous nephropathy coincident with cancer ...
Dan Zhang +5 more
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Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]
, 2002 Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Fink, E. +6 more
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The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]
Journal of NephropharmacologyMembranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar +3 more
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Secondary membranous nephropathy associated with guillain-barré syndrome. [PDF]
, 2013 Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in adults. It may be primary, usually mediated by IgG4 anti-phospholipase A2 autoantibodies or secondary to various other conditions.
Bell, Rodney +4 more
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Treatment of membranous nephropathy: Perspectives on current and future therapies
Frontiers in Nephrology, 2023 Primary membranous nephropathy remains one of the most frequent causes of nephrotic syndrome in adults. It is an autoimmune disorder in which auto-antibodies target antigens at the podocytes cell membrane–basement membrane interface. Our understanding of
Monarch Shah +2 more
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Long-term prognosis in chronic primary glomerulonephritides [PDF]
, 2012 Chronic primary glomerulonephritides (CPGN) is a group of diseases characterised by leakage of proteins and/or erythrocytes into the urine with or without decreased glomerular filtration rate (GFR), hypertension, oedema, hyperlipidemia and low serum ...
Bjørneklett, Rune Oskar
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Genetics of membranous nephropathy [PDF]
Nephrology Dialysis Transplantation, 2017 An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and additional evidence for a genetic component to MN was suggested in 1984 in reports of familial MN. In 2009, a pathogenic autoantibody was identified against the phospholipase A2 receptor 1 (PLA2R1).
Gupta, Sanjana +6 more
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Acute Kidney Injury in A Patient with Membranous Nephropathy – A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2013 Acute Kidney Injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. Acute Kidney Injury is an important complication of membranous nephropathy. Causes are varied and include hypovolumia,
Uday Bande +4 more
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Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
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