Results 21 to 30 of about 15,079 (253)
Perspectives in membranous nephropathy [PDF]
AbstractThe identification of the phospholipase A2 receptor 1 (PLA2R) and thrombospondin type-1 domain-containing protein 7A (THSD7A) as podocyte antigens in adult patients with membranous nephropathy (MN) has strongly impacted both experimental and clinical research on this disease. Evidence has been furnished that podocyte-directed autoantibodies can
Nicola M. Tomas +2 more
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Genetics of membranous nephropathy [PDF]
An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and additional evidence for a genetic component to MN was suggested in 1984 in reports of familial MN. In 2009, a pathogenic autoantibody was identified against the phospholipase A2 receptor 1 (PLA2R1).
Gupta, Sanjana +6 more
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Treatment of membranous nephropathy: Perspectives on current and future therapies
Primary membranous nephropathy remains one of the most frequent causes of nephrotic syndrome in adults. It is an autoimmune disorder in which auto-antibodies target antigens at the podocytes cell membrane–basement membrane interface. Our understanding of
Monarch Shah +2 more
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Acute Kidney Injury in A Patient with Membranous Nephropathy – A Case Report [PDF]
Acute Kidney Injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. Acute Kidney Injury is an important complication of membranous nephropathy. Causes are varied and include hypovolumia,
Uday Bande +4 more
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Primary Membranous Glomerulonephritis in a Young Patient with Proteinuria
Membranous nephropathy is a common form of glomerulonephritis that typically presents with nephrotic syndrome between the 3rd and 5th decades and one-third of patients experience spontaneous remission.
Ece Ünal Çetin, Adil Uğur Çetin
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Primary Membranous Nephropathy [PDF]
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are renal limited (primary MN, PMN) and 20% are associated with other systemic diseases or exposures (secondary MN). This review focuses only on PMN.
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Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer +5 more
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Background Dimercaptosuccinic acid (DMSA) therapy is a kind of chelation therapy for patients with Wilson ‘s disease (WD). While there have been reports of side effects associated with DMSA, the development of membranous nephropathy as a result of this ...
Xiang Li, FengXin Hu, Gaosi Xu
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Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report
Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region.
Roald Vissing-Uhre +3 more
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Abstract Membranous nephropathy (MN) is a glomerular disease characterized by proteinuria, usually in a nephrotic range, and variable natural course. The etiology is unknown in many cases, while in some patients, MN may be secondary to infection, to other diseases, or to exposure to drugs and toxic substances.
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