Results 21 to 30 of about 105,016 (295)

IMMUNODIAGNOSIS IN MEMBRANOUS NEPHROPATHY

Wiadomości Lekarskie, 2020
One of the diseases leading to chronic end-stage renal disease is membranous nephropathy (MN). The main cause of this disease is the formation of antibodies to foreign and native antigens. Membranous nephropathy can be conventionally divided into 2 types: primary form (when the primary disease is unknown) and secondary form.
Magdalena, Ratajczak, Ewa, Poleszak, Tomasz, Chrościcki   +2 more
openaire   +3 more sources

The value of repeat kidney biopsy during an atypical course of membranous nephropathy

BMC Nephrology, 2022
Background The clinical trajectory for patients with primary membranous nephropathy ranges widely from spontaneous remission to a rapid decline in kidney function.
Sumaiya Ahmed, David Massicotte-Azarniouch, Mark Canney, Clare Booth, Paula Blanco, Gregory L. Hundemer   +5 more
doaj   +1 more source

Membranous Nephropathy: Current Understanding in The Light of New Advances [PDF]

, 2023
Membranous nephropathy is the most common cause of primary nephrotic syndrome in adults. The most important mech-anism in its pathogenesis is loss of immune tolerance.
Baloglu, Ismail, Fervenza, Fernando C., Hakan Ozer, Turkmen, Kultigin, Ozer, Hakan, Fernando C Fervenza, Kultigin Turkmen, Ismail Baloglu   +7 more
core   +1 more source

Immunology of membranous nephropathy [PDF]

F1000Research, 2019
Accounting for about 20 to 50% of cases of primary nephrotic syndrome, membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. A rat model created nearly 60 years ago to research the primary MN disorder, Heymann nephritis, has provided us with a plethora of important information.
Shin'ichi Akiyama, Enyu Imai, Shoichi Maruyama   +2 more
openaire   +2 more sources

Perspectives in membranous nephropathy [PDF]

Cell and Tissue Research, 2021
AbstractThe identification of the phospholipase A2 receptor 1 (PLA2R) and thrombospondin type-1 domain-containing protein 7A (THSD7A) as podocyte antigens in adult patients with membranous nephropathy (MN) has strongly impacted both experimental and clinical research on this disease. Evidence has been furnished that podocyte-directed autoantibodies can
Nicola M. Tomas, Tobias B. Huber, Elion Hoxha   +2 more
openaire   +2 more sources

Genetics of membranous nephropathy [PDF]

Nephrology Dialysis Transplantation, 2017
An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and additional evidence for a genetic component to MN was suggested in 1984 in reports of familial MN. In 2009, a pathogenic autoantibody was identified against the phospholipase A2 receptor 1 (PLA2R1).
Gupta, Sanjana, Köttgen, Anna, Hoxha, Elion, Brenchley, Paul, Bockenhauer, Detlef, Stanescu, Horia C., Kleta, Robert   +6 more
openaire   +3 more sources

Rapid diagnosis of membranous nephropathy based on serum and urine Raman spectroscopy combined with deep learning methods

Scientific Reports, 2023
Membranous nephropathy is the main cause of nephrotic syndrome, which has an insidious onset and may progress to end-stage renal disease with a high mortality rate, such as renal failure and uremia.
Xueqin Zhang, Xue Song, Wenjing Li, Cheng Chen, Miriban Wusiman, Li Zhang, Jiahui Zhang, Jinyu Lu, Chen Lu, Xiaoyi Lv   +9 more
doaj   +1 more source

Post-Transplant Thrombotic Microangiopathy due to a Pathogenic Mutation in Complement Factor I in a Patient With Membranous Nephropathy: Case Report and Review of Literature

Frontiers in Immunology, 2022
Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia and organ injury occurring due to endothelial cell damage and microthrombi formation in small vessels.
Maryam Saleem, Sana Shaikh, Zheng Hu, Nicola Pozzi, Anuja Java   +4 more
doaj   +1 more source

Hyperlipidemia in membranous nephropathy. [PDF]

Clin Kidney J
ABSTRACT Membranous nephropathy (MN) is a common glomerular disease leading to nephrotic syndrome in adults, clinically characterized by massive proteinuria, hypoalbuminemia, and prominent hyperlipidemia. Growing evidence suggests that hyperlipidemia is not merely a secondary consequence of MN, but may also play a critical role in the
Zhang M, Liu WL, Xu G, Dong L.
europepmc   +4 more sources

Clinicopathological features in membranous nephropathy with cancer: A retrospective single-center study and literature review

The International Journal of Biological Markers, 2019
Background: Membranous nephropathy is the most common glomerular disease related to malignancy. However, it is difficult to distinguish between true malignancy-related membranous nephropathy and idiopathic membranous nephropathy coincident with cancer ...
Dan Zhang, Chong Zhang, Fan Bian, Wenzhu Zhang, Gengru Jiang, Jun Zou   +5 more
doaj   +1 more source