Results 1 to 10 of about 40,691 (111)

Hypokalemic distal tubulopathy secondary to PLA2R-positive membranous nephropathy: an exceptional case [PDF]

Glomerular Diseases
Introduction: Primary membranous nephropathy, one of the most common primary nephrotic syndromes in adults, rarely has tubular involvement.
Thanawat Vongchaiudomchoke, Boonyarit Cheunsuchon, Nuttaya Wachiraphansakul   +2 more
doaj   +2 more sources

Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in Idiopathic Membranous Nephropathy [PDF]

Frontiers in Immunology, 2022
BackgroundThe anti-phospholipase A2 receptor (PLA2R) antibody is a non-invasive diagnostic tool and prognosis predictor of idiopathic membranous nephropathy (IMN). Baseline hypercholesterolemia independently predicts proteinuria outcomes in IMN patients.
Lei Dong, Yue-qiang Li, Shui-ming Guo, Gang Xu, Wang Wei, Min Han   +5 more
doaj   +2 more sources

Neural epidermal growth factor-like 1 expression predicts end-stage renal disease in phospholipase A2 receptor–negative membranous nephropathy: A retrospective cohort stratified by systemic lupus erythematosus [PDF]

Journal of International Medical Research
Background Neural epidermal growth factor-like 1 protein has emerged as a significant antigen in membranous nephropathy, an important cause of nephrotic syndrome in adults.
Qingqing Rao, Yuan Cheng, Shuling Yue, Haiying Song, Wangyang Li, Dongli Qi, Qijun Wan   +6 more
doaj   +2 more sources

Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro [PDF]

Renal Failure, 2022
Background The pathogenesis of primary membranous nephropathy (MN) involves the antibodies against antigens on the cell surface of podocytes, with the majority of M-type phospholipase A2 receptor (PLA2R), and a profound podocyte dysfunction.
Yanfen Li, Juntao Yu, Miao Wang, Zhao Cui, Ming-hui Zhao   +4 more
doaj   +2 more sources

Outcomes of primary membranous nephropathy based on serum anti-phospholipase A2 receptor antibodies and glomerular phospholipase A2 receptor antigen status: a retrospective cohort study

Renal Failure, 2020
Introduction Primary membranous nephropathy (PMN) is associated with the anti-phospholipase A2 receptor (anti-PLA2R) antibody in 70% of cases. Some anti-PLA2R-negative patients have the PLA2R antigen in renal tissue.
Peihong Yin, Junxian Wang, Wenyi Liang, Linda Zhan, Yuanhao Liu, Jian Lin, Xiaohong Chen, Yingqin He, Hongyun Jian, Zhibin Xie, Xiaofan Tan, Qing Ye, Fengxian Huang   +12 more
doaj   +2 more sources

Phospholipase A2 receptor-negative membranous nephropathy presenting as a rare renal manifestation of IgG4-related disease [PDF]

SAGE Open Medical Case Reports
IgG4-related disease is a fibroinflammatory condition characterized by dense lymphoplasmacytic infiltrates rich in IgG4-positive plasma cells affecting multiple organs.
Srikar Sama, Alexander Weickhardt, Preethi Subramanian, Pooja Reddy   +3 more
doaj   +2 more sources

Recurrence of Phospholipase A2 Receptor–Associated Membranous Nephropathy in the Absence of Serum Anti-Phospholipase A2 Receptor Antibodies Reappearance [PDF]

Kidney International Reports
Ilias Bensouna, Marion Delafosse, Claire Cartery, Thomas Stehlé, Clementine Rabate, Fanny Boullenger, David Buob, Jean-Jacques Boffa, Karine Dahan, Emmanuel Esteve   +9 more
doaj   +2 more sources

Hypercoagulability and dyslipidemia in membranous nephropathy with anti-phospholipase A2 receptor antibodies [PDF]

Renal Failure
Michael Kitlinski, Zbigniew Heleniak, Alicja Dębska-Ślizień   +2 more
doaj   +2 more sources

Presence of M-type Phospholipase A2 Receptor Antibody in Membranous Nephropathy

Turkish Journal of Nephrology, 2020
Objective: The presence of autoantibodies against M-type phospholipase A2 receptor (anti-PLA2R) is a characteristic of idiopathic membranous nephropathy (IMN).
Özgür Akın Oto, Halil Yazıcı, Yaşar Çalışkan, Ayşe Serra Artan, Mehmet Şükrü Sever, Egemen Cebeci, Savaş Öztürk, Aydın Türkmen   +7 more
doaj   +1 more source

Phospholipase A2 Receptor Antibody IgG4 Subclass Improves Sensitivity and Specificity in the Diagnosis of Idiopathic Membranous Nephropathy

Kidney & Blood Pressure Research, 2019
Aims: The aim of this study was to develop a new method for detecting anti-phospholipase A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy (IMN).
Biao Huang, Yi Zhang, Liang Wang, Wenwei Xu, Jue Zhang, Qiuhua Zhang, Huiming Sheng, Zhigang Hu   +7 more
doaj   +1 more source