Results 31 to 40 of about 40,300 (234)

Stimulation of receptor-coupled phospholipase A2 by interferon-γ [PDF]

open access: yes, 1992
The biomolecular mechanisms that mediate signal transduction by type 11 (γ) interferon (IFN) are poorly understood. IFN-γ is a potent growth inhibitory cytokine also endowed with antiviral, immunomodulatory, and differentiating activities on various cell
Paolo Cornaglia-Ferraris   +5 more
core   +1 more source

Advances in Pathogenesis of Idiopathic Membranous Nephropathy

open access: yesKidney Diseases, 2020
Background: Membranous nephropathy (MN), a major cause of nephrotic syndrome, has attracted people’s attention in recent years for its growing prevalence.
Zhifeng Xu   +4 more
doaj   +1 more source

Anti-phospholipase A2 receptor antibody and spontaneous remission in membranous nephropathy [PDF]

open access: yes, 2019
Anti-phospholipase A2 receptor antibody; Membranous nephropathy; Spontaneous remissionAnticòs del receptor anti-fosfolipasa A2; Nefropatia membranosa; Remissió espontàniaAnticuerpo del receptor anti-fosfolipasa A2; Nefropatía membranosa; Remisión ...
Agraz Pamplona, Irene   +2 more
core   +1 more source

Value of M-type phospholipase A2 receptor in clinical diagnosis and treatment of membranous nephropathy:recent advances and current controversies

open access: yesLinchuang shenzangbing zazhi, 2021
The sensitivity of serum anti-M-type phospholipase A2 receptor antibodies(anti-PLA2 R Abs)is 70%~80% in idiopathic membranous nephropathy and the specificity over 95%.This article reviewed the latest research advances on the pathogenesis,diagnosis ...
Wang Hui   +3 more
doaj  

A phospholipase A2‐linked receptor for PEDF

open access: yesThe FASEB Journal, 2006
Pigment epithelium‐derived factor (PEDF), a 50‐kDa extracellular serpin, is a neurotrophic and antiangiogenic factor for the retina. Its biological functions are independent from its serine protease inhibition potential. Previously we provided evidence for high affinity PEDF‐binding sites and proteins in retina cell‐surfaces ...
Luigi Notari   +3 more
openaire   +1 more source

Molecular Dynamics Simulation of Paracetamol with A2 Phospholipase [PDF]

open access: yes, 2022
This series of files were used in the preparation of a moelcular dynamics simulation of Paracetamol with the A2 phospholipase receptor to analyse and investigate the behaviour of this interaction.The simulation was conducted using the Gromacs software ...
McKenna, C (via Mendeley Data)
core   +1 more source

Glucocorticoid receptor stabilization: Relative effects of molybdate ion on inactivation by alkaline phosphatase and phospholipase A2 [PDF]

open access: yes, 1983
Glucocorticoid receptors in cytosol preparations from rat liver or mouse L cells are inactivated by phospholipase A2 or calf intestine alkaline phosphatase. Molybdate ion, an inhibitor of a variety of phosphatase enzymes, does not prevent inactivation of
Pratt, William B.   +2 more
core   +1 more source

Coincidence or connection? A patient with concurrent Lane Hamilton Syndrome and idiopathic membranous nephropathy

open access: yesRespiratory Medicine Case Reports, 2021
Lane Hamilton Syndrome is the rare association of idiopathic pulmonary hemosiderosis and Celiac Disease. The definitive pathophysiologic link is unknown, but the syndrome has been described as co-occurring along with other diseases. We describe the first
Scarlett Austin   +6 more
doaj   +1 more source

Expression of Phospholipase A2 Receptor in Pediatric Hepatitis B Virus-Related Membranous Nephropathy [PDF]

open access: yesChildhood Kidney Diseases, 2020
Purpose Hepatitis B virus (HBV) infection is among etiologies of secondary membranous nephropathy (MN) in pediatric patients. We evaluated expression of phospholipase A2 receptor (PLA2R), a specific target antigen of primary MN, in pediatric HBV-related ...
Sung-Eun Choi   +5 more
doaj   +1 more source

Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations. [PDF]

open access: yes, 2011
Elevated plasma levels of lipoprotein-associated phospholipase A(2) (Lp-PLA2) activity have been shown to be associated with increased risk of coronary heart disease and an inhibitor of this enzyme is under development for the treatment of that condition.
Bacanu, S.A.   +32 more
core   +1 more source

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