Results 31 to 40 of about 40,300 (234)
Stimulation of receptor-coupled phospholipase A2 by interferon-γ [PDF]
The biomolecular mechanisms that mediate signal transduction by type 11 (γ) interferon (IFN) are poorly understood. IFN-γ is a potent growth inhibitory cytokine also endowed with antiviral, immunomodulatory, and differentiating activities on various cell
Paolo Cornaglia-Ferraris +5 more
core +1 more source
Advances in Pathogenesis of Idiopathic Membranous Nephropathy
Background: Membranous nephropathy (MN), a major cause of nephrotic syndrome, has attracted people’s attention in recent years for its growing prevalence.
Zhifeng Xu +4 more
doaj +1 more source
Anti-phospholipase A2 receptor antibody and spontaneous remission in membranous nephropathy [PDF]
Anti-phospholipase A2 receptor antibody; Membranous nephropathy; Spontaneous remissionAnticòs del receptor anti-fosfolipasa A2; Nefropatia membranosa; Remissió espontàniaAnticuerpo del receptor anti-fosfolipasa A2; Nefropatía membranosa; Remisión ...
Agraz Pamplona, Irene +2 more
core +1 more source
The sensitivity of serum anti-M-type phospholipase A2 receptor antibodies(anti-PLA2 R Abs)is 70%~80% in idiopathic membranous nephropathy and the specificity over 95%.This article reviewed the latest research advances on the pathogenesis,diagnosis ...
Wang Hui +3 more
doaj
A phospholipase A2‐linked receptor for PEDF
Pigment epithelium‐derived factor (PEDF), a 50‐kDa extracellular serpin, is a neurotrophic and antiangiogenic factor for the retina. Its biological functions are independent from its serine protease inhibition potential. Previously we provided evidence for high affinity PEDF‐binding sites and proteins in retina cell‐surfaces ...
Luigi Notari +3 more
openaire +1 more source
Molecular Dynamics Simulation of Paracetamol with A2 Phospholipase [PDF]
This series of files were used in the preparation of a moelcular dynamics simulation of Paracetamol with the A2 phospholipase receptor to analyse and investigate the behaviour of this interaction.The simulation was conducted using the Gromacs software ...
McKenna, C (via Mendeley Data)
core +1 more source
Glucocorticoid receptor stabilization: Relative effects of molybdate ion on inactivation by alkaline phosphatase and phospholipase A2 [PDF]
Glucocorticoid receptors in cytosol preparations from rat liver or mouse L cells are inactivated by phospholipase A2 or calf intestine alkaline phosphatase. Molybdate ion, an inhibitor of a variety of phosphatase enzymes, does not prevent inactivation of
Pratt, William B. +2 more
core +1 more source
Lane Hamilton Syndrome is the rare association of idiopathic pulmonary hemosiderosis and Celiac Disease. The definitive pathophysiologic link is unknown, but the syndrome has been described as co-occurring along with other diseases. We describe the first
Scarlett Austin +6 more
doaj +1 more source
Expression of Phospholipase A2 Receptor in Pediatric Hepatitis B Virus-Related Membranous Nephropathy [PDF]
Purpose Hepatitis B virus (HBV) infection is among etiologies of secondary membranous nephropathy (MN) in pediatric patients. We evaluated expression of phospholipase A2 receptor (PLA2R), a specific target antigen of primary MN, in pediatric HBV-related ...
Sung-Eun Choi +5 more
doaj +1 more source
Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations. [PDF]
Elevated plasma levels of lipoprotein-associated phospholipase A(2) (Lp-PLA2) activity have been shown to be associated with increased risk of coronary heart disease and an inhibitor of this enzyme is under development for the treatment of that condition.
Bacanu, S.A. +32 more
core +1 more source

