Results 1 to 10 of about 243,754 (245)

Renal tubulointerstitial lesions: a prognostic marker in idiopathic membranous nephropathy [PDF]

open access: yesRenal Failure
Objective To evaluate the impact of renal tubulointerstitial lesions (TIL) on clinical and pathologic outcomes and prognosis in patients with idiopathic membranous nephropathy.Methods A retrospective cohort study was performed on 582 patients with ...
Yonghua Liu   +3 more
doaj   +4 more sources

M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy

open access: yesNew England Journal of Medicine, 2009
BACKGROUND Idiopathic membranous nephropathy, a common form of the nephrotic syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis has been elusive because the target antigen is unknown.
Timothy D Cummins   +2 more
exaly   +3 more sources

Telitacicept monotherapy for refractory idiopathic membranous nephropathy: a case report and literature review [PDF]

open access: yesFrontiers in Medicine
BackgroundPatients with refractory membranous nephropathy (MN) face risks of progressive renal decline and end-stage renal disease (ESRD), with limited treatment efficacy.
Shucheng Chen, Yiqi Huang, Zhongjie Qu
doaj   +3 more sources

Phospholipase A2 receptor (PLA2R) related membranous nephropathy - not specific for idiopathic cases any more [PDF]

open access: yesJournal of Nephropathology, 2018
Context: Membranous nephropathy is among the most common causes of nephrotic syndrome in adults. Evidence Acquisitions: PubMed, EBSCO, Web of Science, directory of open access journals (DOAJ), EMBASE, and Google Scholar with keywords of phospholipase A2 ...
Bahar Bastani
doaj   +3 more sources

Multi-omics insights of immune cells in the risk and prognosis of idiopathic membranous nephropathy. [PDF]

open access: yesCommun Biol
Idiopathic membranous nephropathy (IMN) is the major cause of autoimmune-related nephrotic syndrome. The role immune cells play in the risk and prognosis of IMN remains elusive.
Song X   +8 more
europepmc   +2 more sources

Recurrence of Idiopathic Membranous Nephropathy in the Kidney Allograft: A Systematic Review. [PDF]

open access: yesBiomedicines
Introduction: The recurrence of idiopathic membranous nephropathy (iMN) after kidney transplantation is common, although its exact clinical significance remains unclear.
Panagakis A   +5 more
europepmc   +2 more sources

A dynamic online nomogram for predicting renal outcomes of idiopathic membranous nephropathy. [PDF]

open access: yesBMC Med Inform Decis Mak
Because spontaneous remission is common in IMN, and there are adverse effects of immunosuppressive therapy, it is important to assess the risk of progressive loss of renal function before deciding whether and when to initiate immunosuppressive therapy ...
Wang F   +11 more
europepmc   +2 more sources

Randomised, double-blind study to evaluate the efficacy of rituximab in the treatment of idiopathic membranous nephropathy: A clinical trial protocol. [PDF]

open access: yesPLoS ONE
In Japan, corticosteroid monotherapy has traditionally been recommended as the first-line therapy for membranous nephropathy with nephrotic syndrome.
Shinobu Shimizu   +6 more
doaj   +2 more sources

Association of serum mannose-binding lectin, anti-phospholipase A2 receptor antibody and renal outcomes in idiopathic membranous nephropathy and atypical membranous nephropathy: a single center retrospective cohort study

open access: yesRenal Failure, 2022
Objectives Idiopathic membranous nephropathy (iMN) is a major cause of nephrotic syndrome. Atypical membranous nephropathy (aMN) is a new type of nephropathy in China, characterized by a ‘full-house’ on immunofluorescent examination, that is IgG, IgA ...
Yuchao Zhao   +6 more
doaj   +2 more sources

Single‐dose telitacicept therapy for refractory idiopathic membranous nephropathy: A case series [PDF]

open access: yesClinical Case Reports
Key Clinical Message We report three cases of IMN from our center, where patients received a single dose of telitacicept after showing no response to conventional treatments.
Liping Sun, Fuce Chen, Xinzhou Zhang
doaj   +2 more sources

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