Results 31 to 40 of about 243,754 (245)

Towards the Definition of the Molecular Hallmarks of Idiopathic Membranous Nephropathy in Serum Proteome: A DIA-PASEF Approach

International Journal of Molecular Sciences, 2023
Idiopathic membranous nephropathy (IMN) is a pathologically defined disorder of the glomerulus, primarily responsible for nephrotic syndromes (NS) in nondiabetic adults. The underlying molecular mechanisms are still not completely clarified.
Paolo Previtali, L. Pagani, G. Risca, G. Capitoli, E. Bossi, G. Oliveira, I. Piga, A. Radice, B. Trezzi, R. Sinico, F. Magni, C. Chinello   +11 more
semanticscholar   +1 more source

Phospholipase A2 Receptor Antibodies and Clinical Prognosis in Patients with Idiopathic Membranous Nephropathy: An Updated Systematic Review and Meta-Analysis

Kidney & Blood Pressure Research, 2023
Background: Idiopathic membranous nephropathy (IMN) is the most common form of primary nephrotic syndrome in adults. Antibodies against the M-type phospholipase A2 receptor (PLA2R-ab) are considered as diagnostic biomarkers of IMN.
Jialing Zhang, Zheng Fan, Pei-Xian Wang, A. Zhang   +3 more
semanticscholar   +1 more source

Preliminary study on the efficacy of rituximab in the treatment of idiopathic membranous nephropathy: A single-centre experience

Frontiers in Endocrinology, 2023
Objective To investigate the efficacy of rituximab in the treatment of idiopathic membranous nephropathy (IMN). Methods A total of 77 patients with IMN diagnosed in both our hospital and other hospitals were included in this study; the patients were ...
Ping-bo Chen, M. Mao, Chen-Dan Wang, Xu Zhang, Xiao-Yu Zhao, Yuan-Yuan Gao, Yankun Luo, Yun Zhou   +7 more
semanticscholar   +1 more source

Update on New Antigens in the Pathogenesis of Membranous Nephropathy [PDF]

, 2022
Previously, membranous nephropathies were divided into primary and secondary categories when the exact mechanism or pathogenetic factor were unknown. Approximately 70% accounted for primary membranous nephropathies.
Aris Tsalouchos, Maurizio Salvadori
core   +1 more source

Acute kidney injury in patients with idiopathic membranous nephropathy: influencing factors and prognosis

Renal Failure, 2023
Aim Idiopathic membranous nephropathy (IMN) is a common type of nephrotic syndrome, and is associated with acute kidney injury (AKI). We investigated the association of multiple variables with AKI in patients with IMN.
Zhen-Zhou Li, Meng-Jie Weng, Lizhao Lin, Yi Chen, Jia-Qun Lin, Jiong Cui, De-Wen Jiang, Bin-Bin Fu, Gui-Fen Li, Cai-Ming Chen, Yan-Fang Xu, Jian-Xin Wan   +11 more
semanticscholar   +1 more source

Clinical characteristics and prognosis of patients with idiopathic membranous nephropathy with kidney tubulointerstitial damage

Renal Failure, 2023
Background To investigate the clinical and kidney pathological features and prognosis of idiopathic membranous nephropathy (IMN) with kidney tubulointerstitial damage (TID).
Mengyao Sun, Ping Li, Jianwei Dong, Zhuo Li, Chaofan Li, Shasha Zhang, Bing Chen   +6 more
semanticscholar   +1 more source

Synthetic ACTH in High Risk Patients with Idiopathic Membranous Nephropathy: A Prospective, Open Label Cohort Study. [PDF]

PLoS ONE, 2015
New therapeutic agents are warranted in idiopathic membranous nephropathy. Synthetic ACTH may be advantageous with reported remission rates up to 85% and few side effects.
Anne-Els van de Logt, Charles H Beerenhout, Hans S Brink, Jos J van de Kerkhof, Jack F Wetzels, Julia M Hofstra   +5 more
doaj   +1 more source

The cutoff value and prognosis of anti-PLA2R antibody for idiopathic membranous nephropathy: a single-center retrospective study in China

Renal Failure, 2023
Serum anti-phospholipase A2 receptor (anti-PLA2R) antibody is used for the noninvasive diagnosis of idiopathic membranous nephropathy (IMN). However, the cutoff value of anti-PLA2R antibodies in IMN patients is debatable.
Hongxia Guo, Yao Yao, Jiansuo Zhou, Song Wang, Yue Wang, Dan-Xia Zheng   +5 more
semanticscholar   +1 more source

Deep learning-based framework for the distinction of membranous nephropathy: a new approach through hyperspectral imagery

BMC Nephrology, 2021
Background Common subtypes seen in Chinese patients with membranous nephropathy (MN) include idiopathic membranous nephropathy (IMN) and hepatitis B virus-related membranous nephropathy (HBV-MN). However, the morphologic differences are not visible under
Tianqi Tu, Xueling Wei, Yue Yang, Nianrong Zhang, Wei Li, Xiaowen Tu, Wenge Li   +6 more
doaj   +1 more source

Cyclophosphamide induced early remission and was superior to rituximab in idiopathic membranous nephropathy patients with high anti-PLA2R antibody levels

BMC Nephrology, 2023
Rituximab (RTX) and cyclophosphamide (CYC) based treatments are both recommended as first-line therapies in idiopathic membranous nephropathy (IMN) by KDIGO 2021 guideline. However, the efficacy of RTX vs.
Cheng Xue, Jian Wang, Jin-Yan Pan, Congdie Liang, Chen-Chen Zhou, Jun Wu, Shuwei Song, Linlin Cui, Liming Zhang, Ya-Wei Liu, Bing Dai   +10 more
semanticscholar   +1 more source