Results 51 to 60 of about 243,754 (245)

Clinicopathological features and outcome in elderly patients with idiopathic membranous nephropathy

Renal Failure, 2023
Background Idiopathic membranous nephropathy (IMN) is the leading cause of nephrotic syndrome in the elderly. The treatment of idiopathic membranous nephropathy is quite challenging due to the particularity of elderly patients.
Jin Liang, Wen-Ke Hao, Fangxiao Xia, Zhi Zhao, Yanhua Wu, Feng Yu, Wen-Xue Hu, Xiaowu Fang, Wei Liu   +8 more
semanticscholar   +1 more source

How Does Herbal Medicine Treat Idiopathic Membranous Nephropathy?

Frontiers in Pharmacology, 2020
Idiopathic membranous nephropathy (IMN) has made increasing progress in mechanism and treatment research. Herbal medicine is gradually being accepted as an alternative therapy in treating IMN. However, the intervention mechanism of herbal medicine in the
Zhendong Feng, Zhendong Feng, Wenbin Liu, Han Xue Jiang, Haoran Dai, Chang Gao, Zhaocheng Dong, Yu Gao, Fei Liu, Zihan Zhang, Qihan Zhao, Lei Zhang, Baoli Liu   +12 more
doaj   +1 more source

Idiopathic Nonlupus Full-House Nephropathy: Clinicopathological Presentation and Comparison with Lupus Full-House Nephropathy

Saudi Journal of Kidney Diseases and Transplantation, 2022
Full-house pattern on immunofluorescence (IF) on kidney biopsy in a patient without systemic lupus erythematosus is termed as nonlupus full-house nephropathy (FHN).
Pranab Mahanta, Shahzad Alam, Manzoor Ahmad Parry, Manjuri Sharma, Prodip Doley, Gayatri Pegu, Mastakim Ahmad Mazumder, Hamad Jeelani, Gayatari Pegu   +8 more
doaj   +1 more source

Immunosuppression and outcome in idiopathic membranous nephropathy [PDF]

QJM, 1998
From 1986 to 1996, 53 patients with idiopathic membranous nephropathy (IMN) presented to the Glasgow Royal Infirmary renal unit: 19 (36%) were treated because of progressive disease. We compared outcomes of treated and untreated patients with 37 historical and untreated controls.
C M, Stirling, K, Simpson, J M, Boulton-Jones   +2 more
openaire   +2 more sources

Immunosuppression therapy for idiopathic membranous nephropathy: systematic review with network meta-analysis

JN. Journal of Nephrology (Milano. 1992), 2022
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome in adults. The Kidney Disease Improving Global Outcomes guidelines recommend rituximab or cyclophosphamide and steroids, or calcineurin inhibitor-based therapy. However, there have
B. Bose, Edmund Y. M. Chung, Regina S. Y. Hong, G. Strippoli, David W. Johnson, Wen-Ling Yang, S. Badve, S. Palmer   +7 more
semanticscholar   +1 more source

Elevated plasma interleukin 21 is associated with higher probability and severity of idiopathic membranous nephropathy

Journal of Laboratory Medicine, 2023
Interleukin 21 (IL-21) is a receptor participating in innate immunity and correlates with the activation of innate immune cells. We sought to investigate the role of plasma IL-21 in patients with idiopathic membranous nephropathy (IMN).
Liu Miao, Huang Di, Liang Enyu, Deng Bishun, Huang Huijie, Zhao Zilin, Deng Li, Wang Xiaowan, Lin Haibiao, Bao Kun, Xu Peng, He Min   +11 more
doaj   +1 more source

Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood

International Journal of Molecular Sciences, 2022
The podocyte injury, and consequent proteinuria, that characterize the pathology of idiopathic membranous nephropathy (IMN) is mediated by an autoimmune reaction against podocyte antigens.
C. Chinello, N. de Haan, G. Capitoli, B. Trezzi, A. Radice, L. Pagani, Lucrezia Criscuolo, S. Signorini, S. Galimberti, R. Sinico, M. Wuhrer, F. Magni   +11 more
semanticscholar   +1 more source

Anti-Rituximab Antibodies Occurrence and Clinical Outcomes in Patients With Primary Membranous Nephropathy

Kidney International Reports
Introduction: Rituximab is a first-line treatment for primary membranous nephropathy (pMN), with proven efficacy and safety. The use of monoclonal antibodies such as rituximab can lead to the formation of antidrug antibodies that may interfere with the ...
Marco Allinovi, Maxime Teisseyre, Matteo Accinno, Cecilia Finocchi, Vincent L.M. Esnault, Marion Cremoni, Tommaso Mazzierli, Daniela Lazzarini, Micaela Anna Casiraghi, Céline Fernandez, Kévin Zorzi, Vesna Brglez, Lorenzo Cosmi, Andrea Matucci, Leonardo Caroti, Giulia Antognoli, Calogero Lino Cirami, Alessandra Vultaggio, Barbara Seitz-Polski   +18 more
doaj   +1 more source

Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in Idiopathic Membranous Nephropathy

Frontiers in Immunology, 2022
Background The anti-phospholipase A2 receptor (PLA2R) antibody is a non-invasive diagnostic tool and prognosis predictor of idiopathic membranous nephropathy (IMN). Baseline hypercholesterolemia independently predicts proteinuria outcomes in IMN patients.
Lei Dong, Yue-Qiang Li, Shui-ming Guo, Gang Xu, Wang Wei, Min Han   +5 more
semanticscholar   +1 more source

Controversies in the treatment of idiopathic membranous nephropathy [PDF]

Nature Reviews Nephrology, 2009
Optimum treatment of idiopathic membranous nephropathy is both controversial and challenging. The most extensively studied and frequently used immunosuppressive regimens for this disease comprise alkylating agents plus corticosteroids or ciclosporin. All of these treatment options have inherent problems: they are not effective in all patients, partial ...
Meryl, Waldman, Howard A, Austin
openaire   +2 more sources