Results 71 to 80 of about 243,754 (245)

Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali   +5 more
wiley   +1 more source

Clinical, genetic and molecular aspects of membranous nephropathy [PDF]

open access: yes, 2011
Membranous Nephropathy (MN) is one of the leading causes of end-stage renal disease (ESRD). MN is an autoimmune disease in which autoantibodies target antigens at the level of the glomerular basement membrane.
Stanescu, H.C.
core  

Future embracing: exosomes driving a revolutionary approach to the diagnosis and treatment of idiopathic membranous nephropathy

open access: yesJournal of Nanobiotechnology
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and is associated with high rates of end-stage renal disease. Early detection and precise interventions are crucial for improving patient prognosis and quality of life ...
Lin Wang   +11 more
semanticscholar   +1 more source

Single-Cell Profiling Reveals Transcriptional Signatures and Cell-Cell Crosstalk in Anti-PLA2R Positive Idiopathic Membranous Nephropathy Patients

open access: yesFrontiers in Immunology, 2021
Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) characterized by increased proteinuria, which leads to serious consequences.
Jie Xu   +16 more
semanticscholar   +1 more source

Idiopathic Membranous Nephropathy: An Autoimmune Disease [PDF]

open access: yesSeminars in Nephrology, 2011
For more than 50 years researchers have debated the evidence for an autoimmune basis of human idiopathic membranous nephritis (MN). Work published in the past 2 years has substantially strengthened the belief that MN is indeed an autoimmune disease of the kidney. Autoantibodies of the IgG4 subclass to at least three podocyte membrane proteins including
Sudesh P, Makker, Alfonso, Tramontano
openaire   +2 more sources

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang   +4 more
wiley   +1 more source

Circulating Antibodies against Thrombospondin Type-I Domain-Containing 7A in Chinese Patients with Idiopathic Membranous Nephropathy

open access: yes, 2017
Background and objectives Thrombospondin type-I domain containing 7A (THSD7A) was recently identified as the target antigen in about 10% of patients with M-type phospholipase A2 receptor (PLA2R) negative membranous nephropathy in European and North ...
Liu, Gang   +27 more
core   +1 more source

Helper T Cells in Idiopathic Membranous Nephropathy

open access: yesFrontiers in Immunology, 2021
Idiopathic membranous nephropathy (IMN) is an autoimmune disease in which the immune system produces an antibody response to its own antigens due to impaired immune tolerance.
Qi-Han Zhao   +14 more
semanticscholar   +1 more source

Idiopathic Membranous Nephropathy [PDF]

open access: yesJournal of the American Society of Nephrology, 2010
Understanding the natural history of a disease is crucial in determining whether therapy will be appropriate or useful. Idiopathic membranous nephropathy is a prime example of this guiding principle. It has been known for decades, from studies out of France,1 Italy,2 and elsewhere,3,4 that without treatment, membranous nephropathy follows a course ...
openaire   +1 more source

Rituximab treatment of idiopathic membranous nephropathy [PDF]

open access: yesKidney International, 2008
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome whose pathogenesis may involve B-cell functions. Rituximab is a monoclonal antibody that binds to the CD20 antigen on B cells thereby deleting them. We conducted an open-label pilot trial of rituximab treatment in 15 severely nephrotic patients with proteinuria refractory to ...
Fervenza, F.C.   +11 more
openaire   +2 more sources

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