Results 71 to 80 of about 243,754 (245)
Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis
ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali +5 more
wiley +1 more source
Clinical, genetic and molecular aspects of membranous nephropathy [PDF]
Membranous Nephropathy (MN) is one of the leading causes of end-stage renal disease (ESRD). MN is an autoimmune disease in which autoantibodies target antigens at the level of the glomerular basement membrane.
Stanescu, H.C.
core
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and is associated with high rates of end-stage renal disease. Early detection and precise interventions are crucial for improving patient prognosis and quality of life ...
Lin Wang +11 more
semanticscholar +1 more source
Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) characterized by increased proteinuria, which leads to serious consequences.
Jie Xu +16 more
semanticscholar +1 more source
Idiopathic Membranous Nephropathy: An Autoimmune Disease [PDF]
For more than 50 years researchers have debated the evidence for an autoimmune basis of human idiopathic membranous nephritis (MN). Work published in the past 2 years has substantially strengthened the belief that MN is indeed an autoimmune disease of the kidney. Autoantibodies of the IgG4 subclass to at least three podocyte membrane proteins including
Sudesh P, Makker, Alfonso, Tramontano
openaire +2 more sources
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
Background and objectives Thrombospondin type-I domain containing 7A (THSD7A) was recently identified as the target antigen in about 10% of patients with M-type phospholipase A2 receptor (PLA2R) negative membranous nephropathy in European and North ...
Liu, Gang +27 more
core +1 more source
Helper T Cells in Idiopathic Membranous Nephropathy
Idiopathic membranous nephropathy (IMN) is an autoimmune disease in which the immune system produces an antibody response to its own antigens due to impaired immune tolerance.
Qi-Han Zhao +14 more
semanticscholar +1 more source
Idiopathic Membranous Nephropathy [PDF]
Understanding the natural history of a disease is crucial in determining whether therapy will be appropriate or useful. Idiopathic membranous nephropathy is a prime example of this guiding principle. It has been known for decades, from studies out of France,1 Italy,2 and elsewhere,3,4 that without treatment, membranous nephropathy follows a course ...
openaire +1 more source
Rituximab treatment of idiopathic membranous nephropathy [PDF]
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome whose pathogenesis may involve B-cell functions. Rituximab is a monoclonal antibody that binds to the CD20 antigen on B cells thereby deleting them. We conducted an open-label pilot trial of rituximab treatment in 15 severely nephrotic patients with proteinuria refractory to ...
Fervenza, F.C. +11 more
openaire +2 more sources

