Results 61 to 70 of about 243,754 (245)

Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy

Journal of Translational Medicine, 2022
Background Extracellular vesicle (EV)-microRNAs (miRNAs) are potential biomarkers for various renal diseases. This study attempted to identify the circulating EV-miRNA signature not only for discriminating idiopathic membranous nephropathy (IMN) from ...
In O. Sun, Yun-Ui Bae, Haekyung Lee, Hyoungnae Kim, J. Jeon, H. Noh, Jong-Soo Choi, K. Doh, S. Kwon   +8 more
semanticscholar   +1 more source

Recurrence of Idiopathic Membranous Nephropathy in a Renal Allograft

, 1975
Idiopathic membranous nephropathy, also termed "membranous glomerulonephritis," "extramembranous glomerulonephritis," "Ellis type 2 nephritis," and "epimembranous nephropathy,"1,2 is a well-recognized cause of nephrotic syndrome.
Crosson, John T, Andersen, Robert C, Anderson, W. Robert, Raij, Leopoldo, Wathen, Ronald L, John T. Crosson   +5 more
core   +1 more source

Obinutuzumab and Ofatumumab are More Effective Than Rituximab in the Treatment of Membranous Nephropathy Patients With Anti-Rituximab Antibodies

Kidney International Reports
Introduction: Although rituximab has significantly improved outcomes for patients with membranous nephropathy, response to treatment is not universal and drug resistance can occur.
Maxime Teisseyre, Marco Allinovi, Vincent Audard, Marion Cremoni, Giulia Belvederi, Alexandre Karamé, Matteo Accinno, Julien Duquesne, Vinod Sharma, Céline Fernandez, Kévin Zorzi, Mounir El Maï, Vesna Brglez, Sylvia Benzaken, Vincent L.M. Esnault, Alessandra Vultaggio, Harbir Singh Kohli, Raja Ramachandran, Calogero Lino Cirami, Barbara Seitz-Polski   +19 more
doaj   +1 more source

Complement-coagulation crosstalk in idiopathic membranous nephropathy: The potential pathogenesis and therapeutic perspective.

Autoimmunity Reviews
Idiopathic membranous nephropathy (IMN) is a glomerular disease that is prevalent in elderly males. The pathogenesis of IMN includes abnormal autoimmunity and complement activation, both of which leading to the damage of the glomerular filtration ...
Zi-Kang Liu, Wei Liang, Yang-Bin Pan
semanticscholar   +1 more source

Mechanism of action of Tripterygium wilfordii for treatment of idiopathic membranous nephropathy based on network pharmacology

Renal Failure, 2022
Background Although thunder god vine (Tripterygium wilfordii) has been widely used for treatment of idiopathic membranous nephropathy (IMN), the pharmacological mechanisms underlying its effects are still unclear.
Hong-Hong Shi, Yanjuan Hou, Xiao-Le Su, J. Qiao, Qian Wang, Xiaojiao Guo, Zhihong Gao, Li-Hua Wang   +7 more
semanticscholar   +1 more source

Association of gut microbiota with idiopathic membranous nephropathy

BMC Nephrology, 2022
Background The prevalence of idiopathic membranous nephropathy (IMN) is increasing worldwide and the gut microbiota is recognized to play a role in its pathology.
Mengfei Li, Lixue Wei, Jing Sun, Qian-hao Zhu, He Yang, Yu Zhang, Chao Zhang, Linghui Xi, Rong-Hua Zhao, Xuanyi Du   +9 more
semanticscholar   +1 more source

From KDIGO 2012 towards KDIGO 2021 in idiopathic membranous nephropathy guidelines: what has changed over the last 10 years?

JN. Journal of Nephrology (Milano. 1992), 2022
The recommendations in the Kidney Disease: Improving Global Outcomes (KDIGO) 2021 guidelines regarding Idiopathic Membranous Nephropathy (IMN) management include significant changes as compared to those published in 2012.
S. Stai, Georgios Lioulios, Michalis Christodoulou, A. Papagianni, M. Stangou   +4 more
semanticscholar   +1 more source

Value of M-type phospholipase A2 receptor in clinical diagnosis and treatment of membranous nephropathy:recent advances and current controversies

Linchuang shenzangbing zazhi, 2021
The sensitivity of serum anti-M-type phospholipase A2 receptor antibodies（anti-PLA2 R Abs）is 70%～80% in idiopathic membranous nephropathy and the specificity over 95%.This article reviewed the latest research advances on the pathogenesis,diagnosis ...
Wang Hui, Jiang Man, Zhang Di, Wang Yu-qin   +3 more
doaj  

Serum anti-phospholipase A2 receptor antibody in pathological diagnosis of type 2 diabetes mellitus patients with proteinuria

Scientific Reports, 2023
Patients with diabetes mellitus complicated with proteinuria can be diabetic nephropathy (DN), diabetic complicated with non-diabetic kidney disease (NDKD), or DN with NDKD.
Huanhuan Zhang, Yuanjie Zhu, Zhijuan Hu, Qiong Liu   +3 more
doaj   +1 more source

PLA2R-IgG4 antibody as a predictive biomarker of treatment effectiveness and prognostic evaluation in patients with idiopathic membranous nephropathy: a retrospective study

PeerJ, 2022
Background The Kidney Disease Improving Global Outcomes (KDIGO) 2021 guidelines recommend Rituximab (RTX) as the first-line therapy and phospholipase A2 receptor (PLA2R) antibody as a biomarker for remission and prognosis in patients with idiopathic ...
Yiqing Huang, Junyi Zhou, Ke-Zhi Zhou, Biao Huang, Jing Xue, Xi-Ran Zhang, B. Liu, Zhi-Jian Zhang, Leting Zhou, Ting Cai, Yi Zhang, Zhi-Gang Hu, Liang Wang, Xiao-Bin Liu   +13 more
semanticscholar   +1 more source