Results 41 to 50 of about 1,619,431 (240)

Economic Benefit of Anti-PLA2R Antibody Testing in the Diagnosis of Membranous Nephropathy: A Single-Center Cost Analysis

Turkish Journal of Nephrology
Background: This study aimed to evaluate the financial impact of using anti-phospholipase A2 receptor antibody testing instead of kidney biopsy for diagnosing membranous nephropathy.
Asil Demirezen, Nuri Alperen Malkoç, Ömer Faruk Akçay, Saliha Yıldırım, Emre Yaşar, Sena Türkmen, Emre Yaşar, Sena Türkmen, Özlem Gülbahar, Betül Öğüt, İpek Işık Gönül, Galip Güz, Ülver Derici, Yasemin Erten, Kadriye Altok, Özant Helvacı   +15 more
doaj   +1 more source

Inhibitory potential of important phytochemicals from Pergularia daemia (Forsk.) chiov., on snake venom (Naja naja)

Journal of Genetic Engineering and Biotechnology, 2016
Pergularia daemia (Forsk.) chiov., is a milk weed of Asclepiadaceae family. In the present study β-sitosterol, β-amyrin, α-amyrin and lupeol were identified in the leaf by GC–MS.
S.T.V. Raghavamma, Nadendla Rama Rao, Garikapati Devala Rao   +2 more
doaj   +1 more source

Autoantibodies against phospholipase A2 receptor in Korean patients with membranous nephropathy. [PDF]

PLoS ONE, 2013
The data were presented in abstract form at the 45(th) meeting of the American Society of Nephrology, October 30-November 04 2012, San Diego, CA, USA. Circulating autoantibodies against M-type phospholipase A2 receptor (PLA2R) are important pathogenic ...
Yun Jung Oh, Seung Hee Yang, Dong Ki Kim, Shin-Wook Kang, Yon Su Kim   +4 more
doaj   +1 more source

Anti-phospholipase A2 Receptor Antibody and Immunosuppression in Membranous Nephropathy [PDF]

Journal of the American Society of Nephrology, 2015
In the 6 years since the discovery of anti-phospholipase A2 receptor (anti-PLA2R) antibodies in the majority of patients with primary membranous nephropathy (MN),1 our understanding of the role of anti-PLA2R in clinical disease has evolved rapidly. The initial small retrospective clinical studies indicated that anti-PLA2R levels could be modulated by ...
openaire   +2 more sources

Secondary membranous nephropathy in a patient with myasthenia gravis without thymic disease, and partial remission induced by adrenocorticotropic hormone therapy

SAGE Open Medical Case Reports, 2019
Membranous glomerulonephritis is the most common glomerular disease in adults. Its primary form has been characterized with formation of phospholipase A2 receptor antibodies.
Ramy M Hanna, Farid Arman, Umut Selamet, William D Wallace, Marina Barsoum, Anjay Rastogi, Niloofar Nobakht, Perry Shieh   +7 more
doaj   +1 more source

Anti-Phospholipase A2 Receptor Antibodies and the Pathogenesis of Membranous Nephropathy [PDF]

Nephron Clinical Practice, 2014
Since the early 2000s, considerable advances have been achieved in the understanding of molecular pathomechanisms of human membranous nephropathy (MN), inspired by studies of Heymann nephritis, a faithful experimental model. These studies led to the identification of neutral endopeptidase, the type-M phospholipase A₂ receptor ...
Pierre, Ronco, Hanna, Debiec
openaire   +2 more sources

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Negative anti-phospholipase A2 receptor antibody status at three months predicts remission in primary membranous nephropathy

Renal Failure, 2022
Background The value of anti-phospholipase A2 receptor antibody (anti-PLA2R ab) monitoring at 3 months after diagnosis in membranous nephropathy (MN) remains uncertain. Methods We retrospectively examined the outcome on 1 August 2020 of 59 adult patients
Gabriel Stefan, Simona Stancu, Adrian Zugravu, Otilia Popa, Dalia Zubidat, Nicoleta Petre, Gabriel Mircescu   +6 more
doaj   +1 more source

sj-pdf-1-cjk-10.1177_20543581211052729 – Supplemental material for Qualitative and Quantitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody: One-Year Experience in Quebec’s Reference Center

, 2021
Supplemental material, sj-pdf-1-cjk-10.1177_20543581211052729 for Qualitative and Quantitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody: One-Year Experience in Quebec’s Reference Center by Simon Leclerc, Karim Benkirane, Annie ...
Simon Leclerc (1862623), Caroline Lamarche (11609301), Louis-Philippe Laurin (324428), Annie-Claire Nadeau-Fredette (8033531), Naoual Elftouh (4095028), Virginie Royal (11609298), Karim Benkirane (11609295), Jean-Philippe Lafrance (4095019), Vincent Pichette (3990317)   +8 more
core   +1 more source

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source