Results 41 to 50 of about 40,300 (234)

Molecular Dynamics Simulation of Aspirin with A2 Phospholipase [PDF]

, 2022
This series of files were used in the preparation of a moelcular dynamics simulation of Aspirin with the A2 phospholipase receptor to analyse and investigate the behaviour of this interaction.The simulation was conducted using the Gromacs software and ...
McKenna, C (via Mendeley Data)
core   +1 more source

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

Nature Communications, 2020
Membranous nephropathy (MN) is a rare autoimmune disease of podocyte-directed antibodies, such as anti-phospholipase A2 receptor. Here, the authors report a genome-wide association study for MN and identify two previously unreported loci encompassing the
Jingyuan Xie, Lili Liu, Nikol Mladkova, Yifu Li, Hong Ren, Weiming Wang, Zhao Cui, Li Lin, Xiaofan Hu, Xialian Yu, Jing Xu, Gang Liu, Yasar Caliskan, Carlo Sidore, Olivia Balderes, Raphael J. Rosen, Monica Bodria, Francesca Zanoni, Jun Y. Zhang, Priya Krithivasan, Karla Mehl, Maddalena Marasa, Atlas Khan, Fatih Ozay, Pietro A. Canetta, Andrew S. Bomback, Gerald B. Appel, Simone Sanna-Cherchi, Matthew G. Sampson, Laura H. Mariani, Agnieszka Perkowska-Ptasinska, Magdalena Durlik, Krzysztof Mucha, Barbara Moszczuk, Bartosz Foroncewicz, Leszek Pączek, Ireneusz Habura, Elisabet Ars, Jose Ballarin, Laila-Yasmin Mani, Bruno Vogt, Savas Ozturk, Abdülmecit Yildiz, Nurhan Seyahi, Hakki Arikan, Mehmet Koc, Taner Basturk, Gonca Karahan, Sebahat Usta Akgul, Mehmet Sukru Sever, Dan Zhang, Domenico Santoro, Mario Bonomini, Francesco Londrino, Loreto Gesualdo, Jana Reiterova, Vladimir Tesar, Claudia Izzi, Silvana Savoldi, Donatella Spotti, Carmelita Marcantoni, Piergiorgio Messa, Marco Galliani, Dario Roccatello, Simona Granata, Gianluigi Zaza, Francesca Lugani, GianMarco Ghiggeri, Isabella Pisani, Landino Allegri, Ben Sprangers, Jin-Ho Park, BeLong Cho, Yon Su Kim, Dong Ki Kim, Hitoshi Suzuki, Antonio Amoroso, Daniel C. Cattran, Fernando C. Fervenza, Antonello Pani, Patrick Hamilton, Shelly Harris, Sanjana Gupta, Chris Cheshire, Stephanie Dufek, Naomi Issler, Ruth J. Pepper, John Connolly, Stephen Powis, Detlef Bockenhauer, Horia C. Stanescu, Neil Ashman, Ruth J. F. Loos, Eimear E. Kenny, Matthias Wuttke, Kai-Uwe Eckardt, Anna Köttgen, Julia M. Hofstra, Marieke J. H. Coenen, Lambertus A. Kiemeney, Shreeram Akilesh, Matthias Kretzler, Lawrence H. Beck, Benedicte Stengel, Hanna Debiec, Pierre Ronco, Jack F. M. Wetzels, Magdalena Zoledziewska, Francesco Cucca, Iuliana Ionita-Laza, Hajeong Lee, Elion Hoxha, Rolf A. K. Stahl, Paul Brenchley, Francesco Scolari, Ming-hui Zhao, Ali G. Gharavi, Robert Kleta, Nan Chen, Krzysztof Kiryluk   +119 more
doaj   +1 more source

Anti-phospholipase A2 Receptor Antibody-Positive Membranous Glomerulopathy due to Anti-Koch’s Therapy in a Tuberculosis Patient

Saudi Journal of Kidney Diseases and Transplantation, 2021
Tuberculosis (TB)-associated glomerulonephritis is difficult to diagnose that usually presents with hematuria, proteinuria, edema, hypertension, or renal insufficiency, which is similar to symptoms of primary glomerulonephritis.
Manish R. Balwani, Amit S. Pasari, Amol Bhawane, Priyanka Tolani   +3 more
doaj   +1 more source

Daratumumab for multidrug-resistant phospholipase-A2 receptor–related membranous nephropathy [PDF]

Kidney International, 2022
Contains fulltext : 249419.pdf (Publisher’s version ) (Open Access)
Vink, C.H., van Cranenbroek, B., van der Heijden, J.W., Koenen, H.J.P.M., Koenen, H.J.P.M., Wetzels, J.F.M.   +5 more
openaire   +4 more sources

The significance of anti-phospholipase receptor antibodies in a patient with membranous nephropathy

Saudi Journal of Kidney Diseases and Transplantation, 2020
Membranous nephropathy (MN) is the major cause of nephrotic syndrome in adults and may be secondary to systemic lupus erythematosus or malignancy in 25% of patients.
Jayaprakash R Dasari, Pallavi Reddy, Yeshwanter Radhakrishnan, Nikhil Nair, Ronith Chakraborty, Lena Nemer, Rupesh Raina   +6 more
doaj   +1 more source

Economic Benefit of Anti-PLA2R Antibody Testing in the Diagnosis of Membranous Nephropathy: A Single-Center Cost Analysis

Turkish Journal of Nephrology
Background: This study aimed to evaluate the financial impact of using anti-phospholipase A2 receptor antibody testing instead of kidney biopsy for diagnosing membranous nephropathy.
Asil Demirezen, Nuri Alperen Malkoç, Ömer Faruk Akçay, Saliha Yıldırım, Emre Yaşar, Sena Türkmen, Emre Yaşar, Sena Türkmen, Özlem Gülbahar, Betül Öğüt, İpek Işık Gönül, Galip Güz, Ülver Derici, Yasemin Erten, Kadriye Altok, Özant Helvacı   +15 more
doaj   +1 more source

Inhibitory potential of important phytochemicals from Pergularia daemia (Forsk.) chiov., on snake venom (Naja naja)

Journal of Genetic Engineering and Biotechnology, 2016
Pergularia daemia (Forsk.) chiov., is a milk weed of Asclepiadaceae family. In the present study β-sitosterol, β-amyrin, α-amyrin and lupeol were identified in the leaf by GC–MS.
S.T.V. Raghavamma, Nadendla Rama Rao, Garikapati Devala Rao   +2 more
doaj   +1 more source

Autoantibodies against phospholipase A2 receptor in Korean patients with membranous nephropathy. [PDF]

PLoS ONE, 2013
The data were presented in abstract form at the 45(th) meeting of the American Society of Nephrology, October 30-November 04 2012, San Diego, CA, USA. Circulating autoantibodies against M-type phospholipase A2 receptor (PLA2R) are important pathogenic ...
Yun Jung Oh, Seung Hee Yang, Dong Ki Kim, Shin-Wook Kang, Yon Su Kim   +4 more
doaj   +1 more source

Anti-phospholipase A2 Receptor Antibody and Immunosuppression in Membranous Nephropathy [PDF]

Journal of the American Society of Nephrology, 2015
In the 6 years since the discovery of anti-phospholipase A2 receptor (anti-PLA2R) antibodies in the majority of patients with primary membranous nephropathy (MN),1 our understanding of the role of anti-PLA2R in clinical disease has evolved rapidly. The initial small retrospective clinical studies indicated that anti-PLA2R levels could be modulated by ...
openaire   +2 more sources

Anti-Phospholipase A2 Receptor Antibodies and the Pathogenesis of Membranous Nephropathy [PDF]

Nephron Clinical Practice, 2014
Since the early 2000s, considerable advances have been achieved in the understanding of molecular pathomechanisms of human membranous nephropathy (MN), inspired by studies of Heymann nephritis, a faithful experimental model. These studies led to the identification of neutral endopeptidase, the type-M phospholipase A₂ receptor ...
Pierre, Ronco, Hanna, Debiec
openaire   +2 more sources