Results 61 to 70 of about 1,619,431 (240)

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Anti-glomerular basement membrane disease superimposed on membranous nephropathy after coronavirus disease 2019: A case report

Journal of International Medical Research
Membranous nephropathy concurrent with anti-glomerular basement membrane disease is rarely reported. Acute kidney injury is prominent when these diseases coexist. Coronavirus disease 2019 may trigger this superimposition.
Rongrong Hu, Siqi Tang, Chao Li, Yizhen Wei, Peng Xia, Ke Zheng, Yan Qin   +6 more
doaj   +1 more source

Resistance to Endotoxic Shock in Phospholipase A2 Receptor-deficient Mice [PDF]

Journal of Biological Chemistry, 1997
Mammals possess various types of secretory phospholipase A2, which differ in the primary structure and tissue distribution. The phosholipase A2 receptor (PLA2R) recognizes group IB phospholipase A2 (PLA2-IB) and mediates the PLA2-IB-induced biological responses in non-digestive organs, including eicosanoid production and contraction of airway smooth ...
K, Hanasaki, Y, Yokota, J, Ishizaki, T, Itoh, H, Arita   +4 more
openaire   +2 more sources

Immunohistochemical analysis for thrombospondin type-1 domain-containing 7A (THSD7A) and M-type phospholipase A2 receptor (PLA2R).

, 2015
Immunostaining for THSD7A (a, c, e) and PLA2R (b, d, f) in patients with idiopathic membranous nephropathy (a–d) and secondary membranous nephropathy (e, f). Original magnification: ×400.
Hideo Yasuda (710367), Satoshi Baba (540358), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461)   +4 more
core   +1 more source

Detection of Phospholipase A2 Receptor Related Membranous Nephropathy in Membranous Nephropathy Patient

SVU - International Journal of Medical Sciences, 2020
Background: Membranous glomerulonephritis (MGN) considered as the most common causes of nephrotic syndrome (NS) in the world. Eighty percent of cases are classified as primary MGN.
Alaa Elmaghraby, Wesam M Ismail, Amira Ahmed abdelnaby*, Ali Taha Ali, Eman Muhammed Salaheldeen   +4 more
doaj   +1 more source

The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis

Parasites & Vectors, 2021
Background The NF-κB signalling pathway has been reported to be related to liver fibrosis, and we investigated whether the NF-κB signalling pathway is involved in liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis (CssPLA2 ...
Yin-Juan Wu, Qing He, Mei Shang, Ying-Xuan Yin, Ye Li, Xue Du, Xue-Rong Li   +6 more
doaj   +1 more source

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

, 2008
Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Gilfillan, Alasdair M., Kuehn, Hye Sun, Beaven, Michael A., Swindle, Emily J., Kim, Mi-Sun, Metcalfe, Dean D.   +5 more
core   +2 more sources

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

Clinical value of a serum anti-PLA2R antibody in the diagnosis and monitoring of primary membranous nephropathy in adults

International Journal of Nephrology and Renovascular Disease, 2018
Xueping Wu,1 Lei Liu,1 Yaling Guo,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College, Bengbu, Anhui, People&
Wu X, Liu L, Guo Y, Yang L
doaj  

Phospholipase A2 Receptor Autoantibodies as a Novel Serological Biomarker for Autoimmune Thyroid Disease Associated Nephropathy

Frontiers in Immunology, 2020
Aims: To develop a highly sensitive immunoassay for PLA2R autoantibodies and study the relationship between PLA2R autoantibodies and autoimmune thyroid disease-associated nephropathy.Methods: We applied a highly sensitive time-resolved fluoroimmunoassay ...
Biao Huang, Biao Huang, Yi Zhang, Liang Wang, Qingqing Wu, Ting Li, Jue Zhang, Qiuhua Zhang, Huiming Sheng, Jiandong Bao, Zhigang Hu   +10 more
doaj   +1 more source