Results 81 to 90 of about 40,300 (234)
Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Secretory Phospholipase A2 Receptor-Mediated Activation of Cytosolic Phospholipase A2 in Murine Bone Marrow-Derived Mast Cells [PDF]
The Journal of Immunology, 2000 Abstract The current study examined the signal transduction steps involved in the selective release of arachidonic acid (AA) induced by the addition of secretory phospholipase A2 (sPLA2) isotypes to bone marrow-derived mast cells (BMMC).
A N, Fonteh +3 more
openaire +2 more sources
Activation of phospholipase A2 by cannabinoids Lack of correlation with CNS effects [PDF]
, 1987 Cannabinoids Δ1-tetrahydrocannabinol, cannabinol, cannabidiol and cannabigerol have been shown to affect directly the activity of phospholipase A2 in a cell-free assay.
Evans, A.T. +5 more
core +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
Allergy, EarlyView.ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy
Alimentary Pharmacology &Therapeutics, EarlyView.The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins +6 more
wiley +1 more source
IgG4-Related Disease Is Not Associated with Antibody to the Phospholipase A2 Receptor
International Journal of Rheumatology, 2012 Patients with IgG4-related disease (IgG4-RD) share histopathological characteristics that are similar across affected organs. The finding of infiltration with IgG4+ plasma cells in the proper clinical and histopathological contexts connects a large number of clinical entities that were viewed previously as separate conditions.
Khosroshahi, Arezou +5 more
openaire +4 more sources
Effect of Phospholipase Digestion and Lysophosphatidylcholine on Dopamine Receptor Binding [PDF]
, 1984 [3H]Spiperone specific binding by microsomal membranes isolated from sheep caudate nucleus is decreased by trypsin and phospholipase A2 (Vipera russeli), but is insensitive to neuraminidase.
Carvalho, A. P. +2 more
core +1 more source
Linchuang shenzangbing zazhiObjectiveTo explore the clinical characteristics， treatment and outcomes of renal cell carcinoma （RCC） combined with phospholipase A2 receptor （PLA2R）-related membranous nephropathy （MN）.MethodsThe clinical and pathological data， diagnosis， treatment ...
Sun Miao-xin +7 more
doaj +3 more sources
Biomarkers of atherosclerotic plaque vulnerability and their clinical significance
Chinese Journal of Contemporary Neurology and Neurosurgery, 2016 Inflammatory reaction plays a crucial role in the occurence and development of atherosclerosis. Both basic and clinical trials have provided evidence that the expression of inflammatory biomarkers are closely related with the degree of atherosclerosis.
Ran LIU +5 more
doaj