Results 71 to 80 of about 40,217 (258)
SVU - International Journal of Medical Sciences, 2020 Background: Membranous glomerulonephritis (MGN) considered as the most common causes of nephrotic syndrome (NS) in the world. Eighty percent of cases are classified as primary MGN.
Alaa Elmaghraby +4 more
doaj +1 more source
Parasites & Vectors, 2021 Background The NF-κB signalling pathway has been reported to be related to liver fibrosis, and we investigated whether the NF-κB signalling pathway is involved in liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis (CssPLA2 ...
Yin-Juan Wu +6 more
doaj +1 more source
BMEMat, EarlyView.Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu +13 more
wiley +1 more source
The genetic and functional basis of three inherited cutaneous and gastrointestinal diseases in humans [PDF]
, 2014 This thesis describes investigations into the genetic basis and pathophysiology of three distinct inherited diseases in humans, two of which are strongly associated to the function of the ectodomain sheddase enzyme ADAM17.
Brooke, Matthew A
core
Molecular Dynamics Simulation of Paracetamol with A2 Phospholipase
, 2022 This series of files were used in the preparation of a moelcular dynamics simulation of Paracetamol with the A2 phospholipase receptor to analyse and investigate the behaviour of this interaction.The simulation was conducted using the Gromacs software ...
McKenna, C (via Mendeley Data)
core +1 more source
Phospholipase A2 inhibitors protect against prion and Abeta mediated synapse degeneration. [PDF]
, 2010 BACKGROUND: An early event in the neuropathology of prion and Alzheimer's diseases is the loss of synapses and a corresponding reduction in the level of synaptophysin, a pre-synaptic membrane protein essential for neurotransmission.
Williams Alun +8 more
core +2 more sources
Frontiers in Medicine, 2018 BackgroundM-type phospholipase A2 receptor (PLA2R) is known as a major antigen on podocytes, which is involved with the pathogenesis of idiopathic membranous nephropathy (iMN).
Weiying Li, Yuliang Zhao, Ping Fu
doaj +1 more source
Frontiers in Immunology, 2020 Aims: To develop a highly sensitive immunoassay for PLA2R autoantibodies and study the relationship between PLA2R autoantibodies and autoimmune thyroid disease-associated nephropathy.Methods: We applied a highly sensitive time-resolved fluoroimmunoassay ...
Biao Huang +10 more
doaj +1 more source
Molecular Dynamics Simulation of Aspirin with A2 Phospholipase
, 2022 This series of files were used in the preparation of a moelcular dynamics simulation of Aspirin with the A2 phospholipase receptor to analyse and investigate the behaviour of this interaction.The simulation was conducted using the Gromacs software and ...
McKenna, C (via Mendeley Data)
core +1 more source
International Journal of Nephrology and Renovascular Disease, 2018 Xueping Wu,1 Lei Liu,1 Yaling Guo,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College, Bengbu, Anhui, People&
Wu X, Liu L, Guo Y, Yang L
doaj