Results 11 to 20 of about 1,619,431 (240)

Expression of phospholipase A2 receptor and IgG4 in patients with membranous nephropathy

Vascular Health and Risk Management, 2018
Lei Liu,1 Baochao Chang,1 Xueping Wu,1 Yaling Guo,1 Yan Pan,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College ...
Liu L, Chang B, Wu X, Guo Y, Pan Y, Yang L   +5 more
doaj   +6 more sources

Phospholipase A2 receptor (PLA2R) related membranous nephropathy - not specific for idiopathic cases any more [PDF]

Journal of Nephropathology, 2018
Context: Membranous nephropathy is among the most common causes of nephrotic syndrome in adults. Evidence Acquisitions: PubMed, EBSCO, Web of Science, directory of open access journals (DOAJ), EMBASE, and Google Scholar with keywords of phospholipase A2 ...
Bahar Bastani
doaj   +3 more sources

Phospholipase A₂ affects the activity of fusicoccin receptors [PDF]

FEBS Letters, 1993
Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors.
ADUCCI, PATRIZIA, Ballio, A, Donini, V, Fogliano, V, Fullone, M. R, MARRA, MAURO   +5 more
openaire   +6 more sources

Circulating anti-phospholipase A2 receptor antibodies as a diagnostic and prognostic marker in Greek patients with idiopathic membranous nephropathy – a retrospective cohort study

Romanian Journal of Internal Medicine, 2019
Introduction. Circulating autoantibodies against phospholipase A2 receptor (anti-PLA2R) are recognized as key elements in the pathogenesis of idiopathic membranous nephropathy.
Provatopoulou Simella, Kalavrizioti Dimitra, Stangou Maria, Kouri Maria-Nikoleta, Kalliakmani Pantellitsa, Papasotiriou Marios, Papachristou Evangelos, Goumenos Dimitrios S., Papagianni Aikaterini   +8 more
doaj   +2 more sources

Phospholipase A2 Receptor Antibody–Positive Pregnancy: A Case Report

American Journal of Kidney Diseases, 2020
Renal course and clinical outcomes in pregnant women with primary membranous nephropathy are not completely understood. In addition, the use of autoantibodies to M-type phospholipase A2 receptor (PLA2R) as a serologic marker throughout pregnancy and postpartum in the mother and baby is not yet fully elucidated.
Mala, Sachdeva, Laurence H, Beck, Ilene, Miller, Vanesa, Bijol, Steven, Fishbane   +4 more
openaire   +3 more sources

Anti-phospholipase A2 receptor antibodies in membranous nephropathy

Kidney Research and Clinical Practice, 2018
Sangho Lee
doaj   +3 more sources

Association of M-Type Phospholipase A2 Receptor Deposition in Kidney Tissue with Treatment Outcomes in Patients with Idiopathic Membranous Nephropathy. [PDF]

J Inflamm Res, 2023
Ning-Qiu Xie,1,* Yu-Lin Zhang,2,* Zi-Li Zheng,1 Quan-Lin Zheng,1 Ruo-Ji Chen1 1Department of Nephrology, Jinjiang Municipal Hospital, Jinjiang, Fujian, 362200, People’s Republic of China; 2Department of Pediatric, Jinjiang Municipal Hospital ...
Xie NQ, Zhang YL, Zheng ZL, Zheng QL, Chen RJ.   +4 more
europepmc   +2 more sources

Idiopathic membranous nephropathy and anti-phospholipase A2 receptor antibodies [PDF]

Journal of Nephropathology, 2013
Implication for health policy/practice/research/medical education: Membranous nephropathy (MN) is a glomerular disease due to subepithelial immune deposits and local complement activation resulting in podocyte injury and proteinuria. Patients with idiopathic (but not secondary) MN had circulating autoantibodies, predominantly of the IgG4 subclass ...
Ali Nayer, Arif Asif
doaj   +3 more sources

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Anti-Phospholipase A2 Receptor Antibody Testing to the Rescue. [PDF]

Indian J Nephrol
Serological testing for M-type anti-phospholipase A2 receptor antibodies (antiPLA2R Ab) has abrogated the need for kidney biopsy to diagnose membranous nephropathy in the appropriate clinical setting. We report a case of a 63-year-old hypertensive male who presented with nephrotic syndrome associated with autosomal dominant polycystic kidney disease ...
Nath AS, Herur S, Taduri G, Guditi S, Kalidindi RK, Murugan P, Nair RR, Ganesh N.   +7 more
europepmc   +3 more sources