Results 81 to 90 of about 221,455 (333)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and rituximab in primary membranous nephropathy.

Kidney International, 2020
A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with primary membranous nephropathy at high risk of progression. We hypothesized that sequential therapy with tacrolimus and rituximab is superior to cyclical alternating ...
G. Fernandez-Juárez, J. Rojas-Rivera, A. van de Logt, Joana Justino, Á. Sevillano, F. Caravaca-Fontán, A. Ávila, C. Rabasco, V. Cabello, A. Varela, M. Díez, G. Martín-Reyes, Marian Goicoechea Diezhandino, L. Quintana, I. Agraz, J. Gomez-martino, M. Cao, A. Rodríguez-Moreno, B. Rivas, C. Galeano, J. Bonet, A. Romera, A. Shabaka, E. Plaisier, M. Espinosa, J. Egido, A. Segarra, G. Lambeau, P. Ronco, J. Wetzels, M. Praga   +30 more
semanticscholar   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

PRIORITY Study: Baseline and Post-Rituximab Immune Profiles in a Pediatric Cohort

Journal of Human Immunity
BackgroundPediatric utilization of rituximab encompasses autoimmune, renal, hematologic, and neurologic conditions. Its association with secondary hypogammaglobulinemia and unmasking of inborn errors of immunity is well recognized.
Dr. Jenny Garkaby, Dr. Andrew Wong-Pack, Dr. Leena Ahmed, Dr. Tania Cellucci, Dr. Dua Meghna, Dr. Rahul Chanchlani, Zaina Khan, Zaeem Nadeem   +7 more
doaj   +1 more source

Effects of rituximab dose on hepatitis B reactivation in patients with resolved infection undergoing immunologic incompatible kidney transplantation

Scientific Reports, 2018
Sensitized patients received desensitization therapy with rituximab for kidney transplantation. However, the impact of rituximab dose on hepatitis B virus (HBV) reactivation is unknown.
Juhan Lee, Jun Yong Park, Deok Gie Kim, Jee Youn Lee, Beom Seok Kim, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim, Kyu Ha Huh   +8 more
doaj   +1 more source

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]

, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core  

No tumor uptake on ⁸⁹Zr-rituximab-PET, concordant with CD20 expression in biopsy.

, 2017
Axial images, from left to right attenuation corrected PET, low dose CT and fused PET/CT image of patient 1. a) 89Zr-rituximab-PET shows no tumor uptake concordant with a CD20-negative liver biopsy. b) Corresponding tumor location on 18F-FDG-PET.
Guus A. M. S. van Dongen (506975), Daphne de Jong (3622187), Danielle J. Vugts (506973), Otto S. Hoekstra (300973), Yvonne W. S. Jauw (3622184), Josée M. Zijlstra (3622181), Sonja Zweegman (482354), Marc C. Huisman (3622178)   +7 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Increasing Operational Capacity and Reducing Costs of Rituximab Administration: A Costing Analysis

ACR Open Rheumatology, 2020
Objective Originator intravenous rituximab is an important rheumatology treatment but is costly, and administration requires several hours. Because biosimilar rituximab may cost less and subcutaneous rituximab requires a shorter visit, both may reduce ...
Zachary S. Wallace, Tyler Harkness, Kimberly G. Blumenthal, Hyon K. Choi, John H. Stone, Rochelle P. Walensky   +5 more
doaj   +1 more source

Pneumocystis pneumonia occurrence and prophylaxis duration in kidney transplant recipients according to perioperative treatment with rituximab

BMC Nephrology, 2020
Background Pneumocystis pneumonia (PCP) is a life-threatening fungal infection that can occur in kidney transplantation (KT) recipients. A growing number of KT recipients are receiving perioperative treatment with rituximab, which is associated with ...
Young Hoon Kim, Jee Yeon Kim, Dong Hyun Kim, Youngmin Ko, Ji Yoon Choi, Sung Shin, Joo Hee Jung, Su-Kil Park, Sung-Han Kim, Hyunwook Kwon, Duck Jong Han   +10 more
doaj   +1 more source