Results 91 to 100 of about 936,141 (267)
Main Street, South River, N.J. [PDF]
, 1912 Color postcard of the lower end of Main Street looking toward the river. Awnings on the right side of the street advertise an Arcade and an Optician. Postcard is captioned in red in the upper left "Main Street, South River, N.J." Back side of card shows ...
core +1 more source
Advanced Science, EarlyView.Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv +13 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun +10 more
wiley +1 more source
RiverSoil organic carbon (C) sequestration and nitrogen (N) and phosphorus (P) burial were measured in two floodplain wetlands' soils of the West Fork of the White River watershed (Indiana, United States) whose catchments differed in land use to better ...
Christopher Craft, Shanze Li
doaj +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Trinity River Basin Master Plan [PDF]
, 2007 TextThis Master Plan for the Trinity River Basin succeeds and updates a series of documents promulgated by the Trinity River Authority over the past 50 years.
Trinity River Authority
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RiverLandslide in reservoirs imposes challenges to reservoir operation and dam safety management practices. The understanding of the landside mechanism during reservoir operation is crucial to landslide‐related risk migration.
Penghai Yin +4 more
doaj +1 more source
Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip
Advanced Science, EarlyView.In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao +3 more
wiley +1 more source
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source