Results 151 to 160 of about 936,141 (267)

Analytical study on plastic loosening zone of weak surrounding rocks tunnel in high cold areas

open access: yesRiver
The analysis of plastic loosening zone of tunnels with cold condition, high in situ stress, and weak stratum is the key scientific problem of tunnel construction in cold areas.
Anrun Li   +3 more
doaj   +1 more source

Interface‐Directed High Fluorescence Efficiency Two‐Dimensional Molecular Crystals With Surface‐Exposed Active Sites

open access: yesAdvanced Science, EarlyView.
Here, we designed the Me‐FBSe molecule and prepared a two‐dimensional molecular crystal via liquid‐liquid interface assembly. The crystal preserves the high photoluminescence quantum while simultaneously ensuring the high‐density surface exposure of active sites.
Shuya Liu   +6 more
wiley   +1 more source

Columbia River Gillnetter ; Vol. 46 (2015) [PDF]

open access: yes
The Columbia River Gillnetter is the pilot of the Lower Columbia River commercial fishing industry, keeping fishermen and the public in touch with today's important ...
Columbia River Gillnetter (Columbia River Fishermen's Protective Union)
core  

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Columbia River Gillnetter ; Vol. 45 (Summer 2014) [PDF]

open access: yes
The Columbia River Gillnetter is the pilot of the Lower Columbia River commercial fishing industry, keeping fishermen and the public in touch with today's important ...
Columbia River Gillnetter (Columbia River Fishermen's Protective Union)
core  

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption

open access: yesAdvanced Science, EarlyView.
This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu   +7 more
wiley   +1 more source

D–A Type Perylene Micelles With Synergistic Charge/Energy Transfer for Dual‐Path ROS Generation and Enhanced Photocatalysis

open access: yesAdvanced Science, EarlyView.
Dual‐state activation of singlet and triplet excitons is achieved in perylene‐based nanomicelles via donor engineering. By synergistically pairing charge transfer with energy transfer pathways, while concurrently enabling pollutant pre‐enrichment, this strategy establishes spatial coupling between efficient ROS generation and rapid mineralization ...
Chenfan Xie   +8 more
wiley   +1 more source

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