Results 101 to 110 of about 355,973 (361)

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon   +20 more
wiley   +1 more source

Once and Future Gulf of Mexico Ecosystem: Restoration Recommendations of an Expert Working Group [PDF]

open access: yes, 2011
The Deepwater Horizon (DWH) well blowout released more petroleum hydrocarbons into the marine environment than any previous U.S. oil spill (4.9 million barrels), fouling marine life, damaging deep sea and shoreline habitats and causing closures of ...
Charles H. Peterson   +17 more
core  

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Integrating regional and local monitoring data and assessment tools to evaluate habitat conditions and inform river restoration. [PDF]

open access: yesEcol Indic, 2021
Mejia FH   +5 more
europepmc   +1 more source

Scaling-Up: A Fifth Year of Restoring Oyster Reefs in Great Bay Estuary, NH 2013 Annual Program Report [PDF]

open access: yes, 2014
The eastern oyster (Crassostrea virginica) in New Hampshire’s Great Bay Estuary has declined in the past decades, with local populations reduced due primarily to disease, excessive siltation, and past over-harvest.
Eckerd, R.   +4 more
core   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu   +11 more
wiley   +1 more source

The Penobscot River, Maine, USA: a Basin-Scale Approach to Balancing Power Generation and Ecosystem Restoration

open access: yesEcology and Society, 2011
Although hydropower is a source of low-carbon energy, without careful consideration and management, dams have the potential to degrade river ecosystems and the goods and services they provide to society.
Jeffrey J. Opperman   +4 more
doaj   +1 more source

Ökosystemrenaturierung und nachhaltiges Management von Flüssen und Feuchtgebieten – Einführung in den Sonderband [PDF]

open access: yes, 2013
The restoration of ecosystems has become a major challenge throughout the world in the 21st century (see comprehensive surveys from, e. g. Temperton et al. 2004, van Andel & Aronson 2006, Walker et al. 2007, and Zerbe & Wiegleb 2009).
Arevalo, Jose Ramon   +3 more
core  

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