Results 141 to 150 of about 58,868 (161)

Impact of the IL-15 superagonist N-803 on lymphatic reservoirs of HIV

JCI Insight
BACKGROUND NK cell function is impaired in people with HIV (PWH), hindering their potential to reduce the lymphoid tissue (LT) reservoir. The IL-15 superagonist N-803 has been shown to enhance NK and T cell function and thus may reduce viral reservoirs ...
Joshua Rhein, Jeffrey G. Chipman, Gregory J. Beilman, Ross Cromarty, Kevin Escandón, Jodi L. Anderson, G. Wieking, Jarrett Reichel, Rodolfo Batres, Alexander Khoruts, Christopher M. Basting, P. Hinderlie, Z. Davis, Anne Eaton, Byron P. Vaughn, Elnaz Eilkhani, J. Safrit, P. Soon-Shiong, J. Baker, Nichole R. Klatt, S. Deeks, Jeffrey S. Miller, T. Schacker   +22 more
semanticscholar   +1 more source

Quality of Life in the Phase 2/3 Trial of N-803 Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin‒Unresponsive Nonmuscle-Invasive Bladder Cancer

Urology Practice
Introduction: In the phase 2/3 study QUILT-3.032 (NCT03022825), the ability of the IL-15RαFc superagonist N-803 (nogapendekin alfa inbakicept) plus bacillus Calmette-Guérin (BCG) to elicit durable complete responses in patients with BCG-unresponsive ...
K. Chamie, Sam S. Chang, E. Kramolowsky, M. Gonzalgo, Megan Huang, Paul Bhar, Patricia Spilman, Lennie Sender, Sandeep Reddy, P. Soon-Shiong   +9 more
semanticscholar   +1 more source

Novel lncRNA 803 related to Marek’s disease inhibits apoptosis of DF-1 cells

Avian Pathology
Marek’s disease (MD) is a neoplastic disease that significantly affects the poultry industry. Long non-coding RNAs (lncRNAs) are crucial regulatory factors in various biological processes, including tumourigenesis.
Shuo Han, Shuang Zhao, Haile Ren, Qianqian Jiao, Xian Wu, Xinrui Hao, Mingchun Liu, Liping Han, Limei Han   +8 more
semanticscholar   +1 more source

Identification and characterization of a meta-cleavage product hydrolase involved in biphenyl degradation from Arthrobacter sp. YC-RL1

Applied Microbiology and Biotechnology, 2019
Yanchun Yan
exaly   +2 more sources

ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII

Acta Pharmacologica Sinica, 2019
Endothelial angiogenesis plays a vital role in recovery from chronic ischemic injuries. ZYZ-803 is a hybrid donor of hydrogen sulfide (H 2 S) and nitric oxide (NO).
Yi-Zhun Zhu, Yicheng Mao
exaly   +2 more sources

Apoptosis of human gastric carcinoma MGC-803 cells induced by a novel Astragalus membranaceus polysaccharide via intrinsic mitochondrial pathways.

International Journal of Biological Macromolecules, 2019
In our previous study, a novel cold-water-soluble polysaccharide (APS4) was isolated from Astragalus membranaceus. This study aimed to evaluate the proliferation inhibition and apoptosis-induced effects of APS4 on human gastric carcinoma MGC-803 cells ...
Juan Yu, Haiyu Ji, Xiao-dan Dong, Ying-ying Feng, An-jun Liu   +4 more
semanticscholar   +1 more source

RADICLELESS 1 (RL1)-mediated nad4 intron 1 splicing is crucial for embryo and endosperm development in rice (Oryza sativa L.).

Biochemical and Biophysical Research Communications - BBRC, 2019
Pentatricopeptide repeat (PPR) proteins are one of the largest protein families in land plants. PPR proteins exhibit sequence-specific RNA-binding activity and are implicated in plant growth and development related processes.
Ming-Wei Wu, Heng Zhao, Jin-Dan Zhang, Lei Guo, Chun-Ming Liu   +4 more
semanticscholar   +1 more source

Investigation of the mixed origins of the MGC-803 cell line reveals that it is a hybrid cell line derived from HeLa

Human Cell, 2023
Meimei Yang, Jing He, Sixuan Xia, Yudong Wang, Jun Xiong, Cong Liao, Nan Li, Sanfu Qu, Chao Shen   +8 more
semanticscholar   +1 more source

Safety and virologic impact of haploidentical NK cells plus IL-2 or N-803 in HIV infection.

Journal of Infectious Diseases
Jeffrey S. Miller, Joshua Rhein, Z. Davis, S. Cooley, David H. McKenna, Jodi L. Anderson, Kevin Escandón, G. Wieking, Jarrett Reichel, Ann Thorkelson, S. Jorstad, J. Safrit, P. Soon-Shiong, Gregory J. Beilman, Jeffrey G. Chipman, T. Schacker   +15 more
semanticscholar   +1 more source

FRA-1 suppresses apoptosis of Helicobacter pylori infected MGC-803 cells

Molecular Biology Reports, 2021
Yang Yang, Benshuai You, Surong Dong, Chenglin Zhou   +3 more
semanticscholar   +1 more source