Results 31 to 40 of about 2,820,589 (269)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
LESIONES MUSCULARES DEPORTIVAS: DIAGNOSTICO POR IMAGENES
Revista Chilena de RadiologíaLa gran mayoría de la patología muscular es de origen traumático y relacionado a la actividad deportiva. Alrededor de un 30% de las lesiones en atletas afectan los músculos: En los últimos años ha habido un importante progreso en el diagnóstico de estas ...
Sara Muñoz Ch.
doaj +1 more source
Diagnostics, 2022 CHEK2 (checkpoint kinase 2; MIM# 604373) is a tumor suppressor gene that encodes a serine threonine kinase involved in pathways such as DNA repair, cell cycle arrest, mitosis, and apoptosis.
Aldo Germani +9 more
doaj +1 more source
Application of the Principle of Maximum Conformality to the Top-Quark Charge Asymmetry at the LHC
, 2014 The Principle of Maximum Conformality (PMC) provides a systematic and process-independent method to derive renormalization scheme- and scale- independent fixed-order pQCD predictions.
Brodsky, Stanley J. +3 more
core +1 more source
Soft-dielectron excess in proton-proton collisions at $\sqrt{s}$ = 13 TeV
, 2020 A measurement of dielectron production in proton-proton (pp) collisions at $\sqrt{s} = 13$ TeV, recorded with the ALICE detector at the CERN LHC, is presented in this Letter. The data set was recorded with a reduced magnetic solenoid field.
ALICE Collaboration
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
$\Lambda_\mathrm{c}^+$ production in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 5.02$ TeV
, 2019 A measurement of the production of prompt $\Lambda_{\rm c}^{+}$ baryons in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 5.02 $ TeV with the ALICE detector at the LHC is reported.
ALICE Collaboration
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Duality and Serre functor in homotopy categories
, 2017 For a (right and left) coherent ring $A$, we show that there exists a duality between homotopy categories ${\mathbb{K}}^{{\rm{b}}}({\rm mod}{\mbox{-}}A^{{\rm op}})$ and ${\mathbb{K}}^{{\rm{b}}}({\rm mod}{\mbox{-}}A)$.
Asadollahi, J. +3 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source