Results 171 to 180 of about 18,612 (273)

The Caribbean, Central and South America Network for HIV Epidemiology: 20 Years of HIV Research in the Region

open access: yesJournal of the International AIDS Society, Volume 29, Issue S3, July 2026.
ABSTRACT Introduction Latin America is a key region in advancing efforts to end the HIV epidemic globally. Despite breakthroughs in HIV treatment and prevention in the last 20 years, as well as region‐wide improvements in health infrastructure and policies, there has been a 13% increase in new acquisitions in Latin America from 2010 to 2024.
Jessica L. Castilho   +95 more
wiley   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

open access: yesMedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong   +14 more
wiley   +1 more source

Consistent Collaborative Vehicle Utilization

open access: yesNetworks, Volume 88, Issue 1, Page 99-121, July 2026.
ABSTRACT Carriers are often reluctant to collaborate with other carriers in delivering goods to customers despite potential cost reductions. A durable collaboration requires attention to more aspects. Carriers typically wish to remain competitive, unconstrained by the collaboration, increasing profits by attracting new customers and withholding ...
Sahand Asgharieh Ahari   +2 more
wiley   +1 more source

Evolution of Long‐Term Social Vulnerability After Tropical Cyclones in the United States

open access: yesGeoHealth, Volume 10, Issue 7, July 2026.
Abstract Tropical cyclones pose a substantial threat to the health and welfare of communities across the United States. While existing research has focused primarily on the short‐term impacts of tropical cyclones, typically within days or months after exposure, there remains a gap in understanding their long‐term effects on the socioeconomic and ...
Lingke Jiang   +3 more
wiley   +1 more source

Diet composition of the Red‐billed curassow (Crax blumenbachii) and its role as seed disperser in the Atlantic Forest: conservation insights

open access: yesRestoration Ecology, Volume 34, Issue 5, July 2026.
Abstract Introduction Forest fragmentation and defaunation are major drivers of biodiversity loss in the Atlantic Forest of Brazil, where 70–90% of tree species depend on animal‐mediated seed dispersal. Reintroduction of large frugivores, such as cracids, is being used to restore species populations and lost ecological functions.
Maria P. M. X. Rufino   +9 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, Volume 604, Issue 13, Page 5391-5420, 1 July 2026.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

open access: yesThe Journal of Physiology, Volume 604, Issue 13, Page 5355-5377, 1 July 2026.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier   +3 more
wiley   +1 more source

Targeting highly attenuated IL-18 to PD-1 for enhanced anti-tumor activity. [PDF]

open access: yesFront Immunol
Zhou X   +4 more
europepmc   +1 more source

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