Motor Cortex Hyperexcitability Is Coupled to Neuromuscular Dysfunction in Aged Mice
Aged mice exhibited impaired motor behavior and neuromuscular hypoexcitability, yet cortical output to muscle was enhanced, and motor cortex layer V pyramidal neurons were hyperexcitable, with altered synaptic inputs and excitability‐related transcriptional changes.
Jose A. Viteri +11 more
wiley +1 more source
Risk management plan adherence and clinical outcomes in patients receiving targeted therapies. [PDF]
Wang LF, Li HL, Huang YH, Yin CH.
europepmc +1 more source
Rapid Extensively Drug-Resistant (XDR) TB Diagnosis: An In-House DNA Biochip for Drug Resistance Detection and Mutation Profiling of <i>Mycobacterium tuberculosis</i>. [PDF]
Jain B, Kulkarni S, Baghel NS.
europepmc +1 more source
Cannabidiol in Adults With Lennox–Gastaut Syndrome: Real‐World Experience
Cannabidiol showed sustained effectiveness and good tolerability in adults with LGS, with high retention over a median follow‐up of 41 months. Treatment was associated with improvement in seizure burden, increased seizure‐free days, fewer seizure‐related hospital admissions, and caregiver‐reported improvement in cognitive and behavioural functioning ...
Pyae Aung +9 more
wiley +1 more source
[Study on the factors influencing treatment adherence in patients with chronic multimorbidity]. [PDF]
Zarza-Arribas M +5 more
europepmc +1 more source
ABSTRACT Objectives Magnetic resonance imaging (MRI) is widely used to support relapse diagnosis in neuromyelitis optica spectrum disorder (NMOSD), yet some patients present with attack‐like symptoms without corresponding lesions. We assessed serum glial fibrillary acidic protein (sGFAP) levels in MRI‐negative attack‐like episodes.
Su‐Hyun Kim +4 more
wiley +1 more source
Measuring urine albumin and total protein. [PDF]
Miller WG +3 more
europepmc +1 more source
Abstract The striatum is a brain region within the basal ganglia that plays a crucial role in generating behaviour and mediating perception. The tail striatum (TS) is a poorly understood striatal domain with predominantly sensory functions. Recent evidence supports that abnormal TS dopamine transmission in dopaminergic disease contributes to sensory ...
Bronwyn Riley +4 more
wiley +1 more source
Correction: Current situation and issues regarding termination of risk management plans in Japan. [PDF]
Kameyama N, Hosaka A, Maeda H.
europepmc +1 more source
Multidimensional maturation of oxytocin neurons: A principal component analysis of postnatal development. [PDF]
Maejima Y +4 more
europepmc +1 more source

