Results 141 to 150 of about 18,612 (273)

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery   +3 more
wiley   +1 more source

Indoor Navigation and Manipulation using a Segway RMP [PDF]

open access: yes, 2014
This project dealt with a Segway RMP, utilizing it in an assistive-technology manner, encompassing navigation and manipulation aspects of robotics. First, background research was conducted to develop a blueprint for the robot. The hardware, software, and
Monahan, Paul Michael   +3 more
core  

Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes

open access: yesGlia, Volume 74, Issue 9, September 2026.
Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani   +5 more
wiley   +1 more source

PENGEMBANGAN SISTEM INFORMASI AKUNTANSI KONSINYASI PADA PT RMP JAYA PERKASA [PDF]

open access: yes, 2015
PENGEMBANGAN SISTEM INFORMASI AKUNTANSI KONSINYASI PADA PT RMP JAYA PERKASA
WINNES, DIGHA   +2 more
core  

Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors

open access: yesGlia, Volume 74, Issue 8, August 2026.
In early brain development, neuronal activity reduces OPC differentiation. Decreased neuronal activity changes oligodendrocyte gene expression, including upregulating glutamate receptor genes. AMPA signaling regulates the final stages of OPC differentiation.
Tessa E. Allen   +4 more
wiley   +1 more source

The Laryngeal Auditory Startle Reflex (LASR): A New Component of the Auditory Startle Response

open access: yesThe Laryngoscope, Volume 136, Issue 8, Page 3514-3518, August 2026.
The auditory startle reflex contains a distinct laryngeal component, termed the laryngeal auditory startle reflex (LASR). In healthy adults, the LASR is modulated by supratentorial influences and habituates to repetitive stimuli. Physiologic and pathologic implications for the LASR as a component of the overall human SR remain to be determined but may ...
Catherine F. Sinclair   +4 more
wiley   +1 more source

Integrated simulation of the impacts of resonant magnetic perturbations on tungsten radiation on EAST

open access: yesNuclear Fusion
A significant reduction of 70% in tungsten (W) radiation intensity has been experimentally observed under resonant magnetic perturbation (RMP) fields on the EAST tokamak.
Z.H. Gao   +9 more
doaj   +1 more source

Post‐Marketing Requirements for Anticancer Drugs Approved in Japan, 2001–2024: A Cross‐Sectional Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT The accelerated development of innovative anticancer therapies has led to the early approval of an increasing number of drugs. However, clinical evidence available at the time of approval is often limited, necessitating additional post‐marketing studies to supplement safety and efficacy data.
Aina Tsuno, Hiroe Kitagaki, Hideki Maeda
wiley   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4344-4363, August 2026.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh   +19 more
wiley   +1 more source

External RMP effect on locked-mode-like instability in helical plasmas [PDF]

open access: yes
0000-0003-3754-897XThe slowing-down mechanism of the locked-mode-like instabilities with and without an island structure is investigated through the effects of an external RMP (resonant magnetic perturbation) on the instabilities. For both instabilities,
YOSHINUMA, Mikiro   +10 more
core  

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