Results 121 to 130 of about 20,565 (264)

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

Pharmacological characterization of RMP-7, a novel bradykinin agonist in smooth muscle

, 1999
RMP-7 is a bradykinin (BK) agonist designed to be resistant to kininases such as angiotensin-converting enzyme (ACE). Pharmacological assays were performed with RMP-7 in isolated guinea-pig ileum and rat mesenteric artery.
Paiva, T. B., Borges, ACR, Therezinha B Paiva, Shimuta, S. I., Ana M.R.B Barbosa, Antonio C.R Borges, Barbosa, AMRB, Suma I Shimuta   +7 more
core   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Rescheduling dense train traffic over complex station interlocking areas

, 2009
Goverde RMP, D'ARIANO, Andrea, Corman F.
core   +2 more sources

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery, Jacob A. Miller, Steven Poelzing, Seth H. Weinberg   +3 more
wiley   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza, Renato W. Martins Sá, Luiza Henrique de Souza, Fernando S. Ramalho, Davi J. A. Moraes   +4 more
wiley   +1 more source

Psychopharmacological Prescribing Patterns Among Italian Adolescents With Anorexia Nervosa: Exploring Real‐World Treatment Practices

European Eating Disorders Review, Volume 34, Issue 6, Page 1626-1636, November 2026.
ABSTRACT Objective To investigate real‐world psychopharmacological prescribing patterns among Italian adolescents with anorexia nervosa (AN) compared with psychiatric controls without eating disorders, and to examine whether AN diagnosis independently predicts medication use after accounting for psychiatric comorbidities.
Marika Orlandi, Arianna Vecchio, Giulia Andorno, Maria Pia Riccio, Cinzia Crispino, Martina Maria Mensi   +5 more
wiley   +1 more source

Integrated simulation of the impacts of resonant magnetic perturbations on tungsten radiation on EAST

Nuclear Fusion
A significant reduction of 70% in tungsten (W) radiation intensity has been experimentally observed under resonant magnetic perturbation (RMP) fields on the EAST tokamak.
Z.H. Gao, S.Y. Dai, P. Qin, Z.X. Wen, Z.C. Lin, Z. Zhou, H.M. Zhang, G.Z. Hao, Y. Feng, D.Z. Wang   +9 more
doaj   +1 more source

Integration of Micro‐CT and XRF Mapping for Multimodal 3D Analysis of Polychrome Wooden Artifacts

X-Ray Spectrometry, Volume 55, Issue 6, Page 834-848, November/December 2026.
ABSTRACT Over the past 5 years, computer applications have become crucial to archeological research. Since the 1990s, the focus has transitioned from data management tools to the development of virtual models. Recently, digital documentation of cultural heritage has gained considerable focus, with 3D modeling of objects.
Josiane E. Cavalcante, Olga Araujo, Alessandra Machado, Roberta M. P. S. Borges, Isis V. N. S. Franzi, Anderson G. de Paula, Roberta Leitão, Marcelino dos Anjos, Renato Freitas, Ricardo T. Lopes, Davi F. Oliveira   +10 more
wiley   +1 more source