Results 121 to 130 of about 58,524 (271)

Has risk management plan system influenced the speed of package insert revisions in Japan?

Frontiers in Medicine
IntroductionThe system of Risk Management Plan in Japan (J-RMP) is a relatively new system, implemented in 2013; thus, its effect on safety measures is still unclear.
Natsuko Kameyama, Natsuko Kameyama, Aoi Hosaka, Hideki Maeda, Hideki Maeda   +4 more
doaj   +1 more source

Pancreatic Adenocarcinoma: Diagnosis by Ultrasound‐Guided Fine‐Needle Aspiration—Cyto‐Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center

Diagnostic Cytopathology, Volume 54, Issue 6, Page 403-416, June 2026.
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
Judith González‐López, Mónica Elizabeth Bauza, Judith Pérez‐Rojas, Cecilia López‐Valdivia, Carlos Zac Romero, Óscar Castells‐Perona, Cristina Ballester‐Ibáñez, Eva Montalvá‐Orón, Rafael López‐Andújar, Lidia Argüello‐Viudez, Mireya Prieto Rodríguez   +10 more
wiley   +1 more source

Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 7, Page 1358-1372, June 2026.
ABSTRACT Background Immersive virtual reality (VR) technology offers a non‐invasive, non‐pharmacological approach to reduce pain perception in patients undergoing diagnostic or interventional procedures. Objective To systematically evaluate the efficacy of immersive VR technology in reducing pain perception during obstetric and gynaecological ...
Jhia Jiat Teh, Filipa Campos, Adam Koczoski, Trisha Valencia, Michael P. Rimmer, Bassel H. Al Wattar   +5 more
wiley   +1 more source

TTX‐S/TTX‐R Na+ Currents Coordinately Fine‐Tune Depolarization/Firing Capability Revealed by Voltage Derivatives/Displacement Current Phase Plots With Dynamic Current‐Clamp Simulation in Rat Visceral Sensory Neurons

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim To investigate how tetrodotoxin‐sensitive (TTX‐S) and tetrodotoxin‐resistant (TTX‐R) Na+ channels coordinately fine‐tune action potential (AP) depolarization and firing capability in rat nodose visceral sensory neurons. Methods APs were recorded by ruptured‐patch current clamp in unmyelinated C‐type and myelinated Ah‐type neurons from ...
Zhang Jing‐ran, Fu Hui‐xiao, Li Xing‐yu, Zhang Hong‐fei, Dou Tian‐min, Li Bai‐yan, Wu Di   +6 more
wiley   +1 more source

The Economic Effects of ‘Excessive’ Financial Deepening

Oxford Bulletin of Economics and Statistics, Volume 88, Issue 3, Page 458-472, June 2026.
ABSTRACT We study the causal implications of high levels of financial deepening for economic development and banking crises in a panel of countries over the past seven decades. We adopt a factor‐augmented heterogeneous difference‐in‐differences estimator and find, in contrast to the existing literature, that very high levels of financial development do
Rachel Cho, Rodolphe Desbordes, Markus Eberhardt   +2 more
wiley   +1 more source

Stress Field and Megathrust Strength in the Western Hellenic Subduction System: Insights From the 2024 Mw 5.9 Strofades Earthquake Sequence, Greece

Geophysical Research Letters, Volume 53, Issue 9, 16 May 2026.
Abstract A M5.9 earthquake occurred on 29 March 2024, offshore near the Strofades Islands, in the western Hellenic Subduction System. Here we present high‐precision earthquake locations and focal mechanisms that suggest the rupture of a NNE‐SSW striking, left‐lateral strike‐slip fault.
G. M. Bocchini, D. Essing, I. Nikolopoulou, A. Dielforder, M. P. Roth, A. Serpetsidaki, E. Sokos, C. P. Evangelidis, R. M. Harrington   +8 more
wiley   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1205-1215, May 2026.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco, Troy D. Wood, Raymond Cha, Jill S. Hochreiter, Susan L. Rosenkranz, Mona Farhad, Kyle R. Whitson, Connor E. Gould, Lauren E. Hill, Linda L. Hale, Philip H. Lindhorst, Diala Ghazal, Charlene R. Taylor, Madiha Quraishi, Suzanne M. Siminski, Yoninah Cramer, Heather L. Sprenger, Gene D. Morse   +17 more
wiley   +1 more source

Telomere Length Is Determined by Intrinsic Factors and Is Shortened During Drought Years in Gallotia galloti

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Telomere dynamics in ectotherms remain poorly understood relative to endotherms, yet are increasingly relevant in the context of climate change. Here, we used model‐averaged GLMMs and hierarchical partitioning to disentangle intrinsic and extrinsic drivers of relative telomere length in the Western‐Canaries Lizard (Gallotia galloti) across a 10‐year ...
Edward Gilbert, Megan L. Power, Annika Wolberg, Rodrigo Megía‐Palma, Anamarija Žagar, Marta López‐Darias, Miguel A. Carretero, Nina Serén, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +9 more
wiley   +1 more source

COMPACTACIÓN DE SUELOS POST-COSECHA MECANIZADA DE UN MONTE DE EUCALIPTUS EN EL PARTIDO DE SAN CAYETANO, BUENOS AIRES, ARGENTINA

Revista do Instituto Florestal
La cosecha mecanizada en sistemas forestales genera daños en los suelos que afectan en forma directa la resistencia mecánica a la penetración (RMP) y la porosidad de los suelos y en forma indirecta la capacidad de crecimiento de las plantas y el ...
Victor Hugo Merani, Matilde Mur , Luciano Larrieu , Daniel Ferro, Facundo Guilino, Juan Manuel Vazquez, Guillermo José Millan, Tatiana Cinquetti, Esteban Iván Pereira, Maria Clara Donadelli, María Florencia Zanardi   +10 more
doaj   +1 more source

Gastrointestinal manifestations following chimeric antigen receptor T‐cell (CAR‐T) 19 therapy in pediatric patients with CD19+ acute lymphoblastic leukemia

JPGN Reports, Volume 7, Issue 2, Page 377-381, May 2026.
Abstract Pediatric patients with CD19+ acute lymphoblastic leukemia (ALL) undergoing chimeric antigen receptor T‐cell (CAR‐T) therapy frequently experience gastrointestinal (GI) complications. A retrospective study analyzed 13 patients (median age: 8 years) treated between January 2020 and January 2024.
Judith Raya Muñoz, Melissa Panesso Romero, Saray Mesonero Cavia, Marta Freixas Bermejo, Vanessa Cabello Ruiz, Marina Álvarez Beltran, Maria Cristina Díaz de Heredia Rubio, Susana Elena Redecillas Ferreiro, Oscar Segarra Canton   +8 more
wiley   +1 more source