Results 41 to 50 of about 7,103,681 (193)

Multimodal Fluorescent MOF@BODIPY Platform: Bridging Sensing and Mechanistic Insight

Chemistry – A European Journal, EarlyView.
ABSTRACT Hybrid metal–organic frameworks (MOFs) that integrate organic chromophores constitute powerful platforms for optical sensing by combining structural order with tunable photophysics. Incorporating photoresponsive chromophores into MOFs enables sensitive probing of guest–framework interactions through well‐defined luminescent signatures. Herein,
Alejandro Cortés‐Villena, Paula Rodrigo‐Martínez, José A. Sáez, Pablo Gaviña, Emilio Pardo, Raquel E. Galian, Sergio Armenta, Héctor Martínez‐Pérez‐Cejuela, José Manuel Herrero‐Martínez   +8 more
wiley   +1 more source

Editorial: RMP: Looking Forward

, 2019
Ninety years! As the first spinoff of the Physical Review launched in 1929, Reviews of ModernPhysics (RMP) has tracked the progress of physics during a time of explosive growth of the field.Originally one journal, the Physical Review has not only split ...
Kalogera, Vicky, Castro Neto, A. H., Aihara, Hiroaki, Ramond, Pierre, Molmer, Klaus, Thielemann, Friedel, Castro Neto, A. H, Grannis, Paul D., Dijkstra, Marjolein, Hebard, Arthur F., Leemans, Wim, Nazarewicz, Witold, Springer, Roxanne, Cheung, Margaret S., Kamien, Randall D., Collins, William D., DiVincenzo, David, Mølmer, Klaus, Brodbar, Debbie, Starace, Anthony F., Klebanov, Igor, Belitz, Dietrich   +21 more
core   +1 more source

Effect of Magnetic Islands on Neoclassical Heat Diffusivity in a Global Tokamak Simulation

Contributions to Plasma Physics, EarlyView.
ABSTRACT Resonant magnetic perturbations (RMPs) alter magnetic field topology via island formation and can modify core transport in toroidal fusion devices. Using the global gyrokinetic particle‐in‐cell code XGC‐S, originally developed for stellarator geometries, we quantify how island topology affects neoclassical heat transport in a circular tokamak ...
Joseph X. Li, Toseo Moritaka, Ryutaro Kanno, Gakushi Kawamura, Robert Hager, C.‐S. Chang   +5 more
wiley   +1 more source

Challenges in Implementing European Regulation on Water Reuse for Sustainable Agriculture

Environmental Policy and Governance, EarlyView.
ABSTRACT The Regulation (EU) 2020/741 on minimum requirements for water reuse is a key policy for sustainable water management under growing water scarcity in Europe. This paper examines expert perspectives on the challenges involved in implementing EU regulation for water reuse in agriculture, aiming to broaden existing research, which is largely ...
Patricia Allgaier, Roberta Maffettone, Kevin Grecksch   +2 more
wiley   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Plasma performance and operational space with an RMP-ELM suppressed edge

Nuclear Fusion
The operational space and global performance of plasmas with edge-localized modes (ELMs) suppressed by resonant magnetic perturbations (RMPs) are surveyed by comparing AUG, DIII-D, EAST, and KSTAR stationary operating points.
C. Paz-Soldan, S. Gu, N. Leuthold, P. Lunia, P. Xie, M.W. Kim, S.K. Kim, N.C. Logan, J.-K. Park, W. Suttrop, Y. Sun, D.B. Weisberg, M. Willensdorfer, the ASDEX Upgrade Team, the DIII-D Team, the EAST Team, the KSTAR Team   +16 more
doaj   +1 more source

Development of a Drift‐Kinetic Simulation Code for Estimating Collisional Transport Affected by RMPs and Radial Electric Field

Contributions to Plasma Physics, 2016
AbstractA drift‐kinetic 8f simulation code is developed for estimating collisional transport in quasi‐steady state of toroidal plasma affected by resonant magnetic perturbations and radial electric field. In this paper, validity of the code is confirmed through several test calculations.
R. Kanno, M. Nunami, S. Satake, S. Matsuoka, H. Takamaru   +4 more
openaire   +2 more sources

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source

Investigation of transient heat flux redistribution caused by rotating n = 2 RMP in ELM mitigation experiments on EAST

Nuclear Fusion
This study investigates the role of rotating n = 2 resonant magnetic perturbation (RMP) in modifying the transient heat flux distribution during edge localized mode (ELM) mitigation on Experimental Advanced Superconducting Tokamak.
G.T. Chen, H. Yang, Y.W. Sun, M.N. Jia, Q. Ma, J.H. Yang, Q.Q. Yang, T.H. Wang, J.Z. Shi, Y.N. Zhang, H. Sheng, X.M. Wu, S. Gu, Z.D. Yang, R.R. Liang, F.C. Zhong   +15 more
doaj   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source