Results 141 to 150 of about 477,009 (248)

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

open access: yesAdvanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost   +9 more
wiley   +1 more source

Disruption of Sulfur Metabolism and Redox Homeostasis in Staphylococcus aureus Using Mechanically Robust Antibiofilm Ti‐Bi Alloys

open access: yesAdvanced Materials Interfaces, EarlyView.
Titanium (Ti) and bismuth (Bi) are selected as alloying elements for the preparation of the Ti‐Bi binary alloy system. Biofilm formation is found to be inhibited by bismuth through the disruption of sulfur metabolism and redox homeostasis, as well as through the direct downregulation of biofilm‐associated proteins.
Lei Shi   +10 more
wiley   +1 more source

Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans. [PDF]

open access: yesNat Commun
Kyriakakis E   +5 more
europepmc   +1 more source

Antimicrobial Multi‐Assay Evaluation of (Al‐Doped ZnO)‐Ag and TiO2‐Ag Nanocoatings: Impact of Direct and Indirect Mechanisms

open access: yesAdvanced Materials Interfaces, EarlyView.
This work explores the antimicrobial action of AZO‐Ag and TiO2‐Ag nanocoatings on plastic, demonstrating good efficacy against highly‐critical antibiotic‐resistant bacteria, yeast, and virus. A multi‐assay approach is here exploited to inspect the contribution of direct and indirect antimicrobial mechanisms, and potential human toxicity is also ...
Damiano Squitieri   +10 more
wiley   +1 more source

Damage Microenvironment Guided Responsive Smart Hydrogel Design for Self‐Regenerative Repair in Chronic Wound Healing

open access: yesAdvanced Materials Interfaces, EarlyView.
Chronic wounds remain a major therapeutic challenge, with VEGF applications hindered by rapid degradation and systemic side effects. Here, a dual‐responsive chitosan–gelatin hydrogel is reported, functionalized with dopamine, glutathione, and MMP‐sensitive motifs, enabling spatiotemporally controlled VEGF release and enhanced biocompatibility, thereby ...
Zhenghui Xiong   +5 more
wiley   +1 more source

Hammerhead ribozymes directed against mRNA of an essential gene inhibit <i>Escherichia coli</i> growth and enhance tetracycline efficacy. [PDF]

open access: yesFront Microbiol
Miszkiewicz-Golec J   +5 more
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

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