Results 151 to 160 of about 2,524,971 (285)

Transcript Identification Using Arrayed Hydrogels With TrapFISH

Advanced Materials Technologies, EarlyView.
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse, Zenon Toprakcioglu, Akhila Denduluri‐Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles   +5 more
wiley   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Machine Learning Enhanced Multimodal Bioelectronics: Advancement Toward Intelligent Healthcare Systems

Advanced Sensor Research, EarlyView.
This review examines recent advancements in multimodal bioelectronics, emphasizing machine learning integration to enhance functionality. The application of machine learning methodologies improving biosignal processing, device adaptability, and diagnostic accuracy is discussed to introduce Machine Learning enhanced bioelectronics as a pathway toward ...
Myoungjae Oh, Enji Kim, Jakyoung Lee, Inhea Jeong, Eunmin Kim, Joonho Paek, Taekyeong Lee, Dayeon Kim, Seung Hyun An, Sumin Kim, Jung Ah Lim, Jang‐Ung Park   +11 more
wiley   +1 more source

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

Advanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger   +6 more
wiley   +1 more source

Single‐Layer Radially Compartmentalized Paper Chip (RCP‐Chip) for Rapid Isothermal Multiplex Detection of SARS‐CoV‐2 Gene Targets

Advanced Sensor Research, EarlyView.
The single‐layer RCP‐Chip enables rapid, multiplexed detection of SARS‐CoV‐2 RNA using RT‐LAMP and gold nanoparticle‐enhanced colorimetric readouts. After sample loading, amplification occurs within radially arranged chambers, allowing simultaneous detection of E and N genes.
Pavithra Sukumar, Alla Saleh, Muhammedin Deliorman, Mohammad A. Qasaimeh   +3 more
wiley   +1 more source

A bacterial Argonaute with noncanonical guide RNA specificity

Proceedings of the National Academy of Sciences of the United States of America, 2016
E. Kaya, K. Doxzen, K. R. Knoll, Ross C. Wilson, Steven C. Strutt, P. Kranzusch, J. Doudna   +6 more
semanticscholar   +1 more source

Cold Plasma Generates a Localized Inflammatory Response and Promotes Muscle Repair

Advanced Therapeutics, EarlyView.
The immediate tissue response to plasma is a pro‐inflammatory response which is characterized by collagen clumping, innate immune cell infiltration, enhanced metabolic processes, and decreased apoptosis. The long‐term tissue response (4‐ and 14‐days) to plasma treatment is characterized by a decreased inflammatory response, decreased adipogenesis, and ...
Carly J. Smith, Amanda R. Watkins, Abigail A. Lucas, Arianna J. Moniodes, Conn Ritchie, Thomas P. Thompson, Thomas P. Schaer, Brendan F. Gilmore, Noreen J. Hickok, Theresa A. Freeman   +9 more
wiley   +1 more source

Diagnostic value of DNA or RNA-based metagenomic next-generation sequencing in lower respiratory tract infections

Heliyon
Objectives: We aimed to evaluate and compare the diagnostic performance of RNA-mNGS and DNA-mNGS workflow in bacterial pneumonia, fungal pneumonia and tuberculosis.
Jiafu Song, Suxia Liu, Yongpeng Xie, Chen Zhang, Caiyun Xu   +4 more
doaj  

Small RNAs and virulence in bacterial pathogens [PDF]

RNA Biology, 2012
Cynthia M. Sharma, Nadja Heidrich
openaire   +2 more sources