Results 241 to 250 of about 532,169 (312)

Oxford Nanopore Technologies RNA sequencing data for investigating epigenetic regulation by phase-variable DNA methyltransferase ModD1 in serogroup B <i>Neisseria meningitidis</i>. [PDF]

Microbiol Resour Announc
Ascari A, Blakeway LV, Walsh CJ, Judd LM, Jennings MP, Seib KL.   +5 more
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

The ribosomal RNA synthesis ratio biomarker in Mycobacterium ulcerans for drug activity evaluation. [PDF]

Infect Dis Poverty
Calvet-Seral J, Sáez-López E, López-Expósito PR, Ferrer-Bazaga S, Vaquero JJ, Ramón-García S, Mendoza-Losana A.   +6 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Sensing the spectrum: diverse stimuli for the NLRP3 inflammasome. [PDF]

Commun Biol
Xiao N, Lu Z, Chen J.
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Small colony variants and cefiderocol resistance in clinical <i>Escherichia coli</i>: an <i>in vitro</i> mechanistic study. [PDF]

Front Microbiol
Syed MA, Pu D, Song R, Zhao J, Cao B.
europepmc   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Human neutrophils recognize group B streptococci <i>via</i> formylated peptide receptors and toll-like receptor 8. [PDF]

Front Immunol
Fiore L, De Gaetano GV, Grasso F, Coppolino F, Famà A, Stifano M, Petrungaro A, Vita F, Quartarone E, Cipollina C, Lentini G, Beninati C.   +11 more
europepmc   +1 more source