Results 271 to 280 of about 2,869,940 (329)

Dual-mode CRISPRa/i for genome-scale metabolic rewiring in Escherichia coli. [PDF]

Nucleic Acids Res
Moon SY, Kim MR, An NY, Noh MH, Lee JY.
europepmc   +1 more source

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

Advanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua, Ning Ding, Yiming Hua, Xiaoke Wang, Yu Xu, Xiangrui Qiao, Xue Shi, Ting Bai, Ying Xiong, Xiaozhen Zhuo, Chong Fan, Juan Zhou, Yue Wu, Junhui Liu, Zuyi Yuan, Ting Li   +15 more
wiley   +1 more source

Implications for OLE RNA as a natural integral membrane RNA. [PDF]

RNA
Lyon SE, Breaker RR.
europepmc   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

A-to-I mRNA editing recodes hundreds of genes in dozens of species and produces endogenous protein isoforms in bacteria. [PDF]

Nucleic Acids Res
Elias E, Gifford I, Didi L, Fargeon O, Arad D, Cohen-Pavon R, Sorek G, Levin L, Melamed D, Aspit L, Barrick JE, Bar-Yaacov D.   +11 more
europepmc   +1 more source

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Epigenetic control of the ferric uptake regulator (Fur) and fumarate nitrate reductase (FNR) master regulatory proteins contributes to <i>Haemophilus influenzae</i> survival during lung infection. [PDF]

mBio
Gil-Campillo C, Euba B, Rodríguez-Arce I, San León D, Marino MC, Asensio-López J, López-López N, Mell JC, Gutiérrez G, Langereis JD, Sánchez-Romero MA, Garmendia J.   +11 more
europepmc   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds

Advanced Science, EarlyView.
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She, Vera Engelbrecht, Jacek Kozuch, Ulf‐Peter Apfel, Sven T. Stripp, Anja Hemschemeier, Thomas Happe   +6 more
wiley   +1 more source