Results 171 to 180 of about 379,319 (234)

Wireless In Situ Catalytic Electron Signaling‐Mediated Transcriptomic Reprogramming for Neuron Regeneration via Adaptable Antennas

Advanced Science, EarlyView.
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao, Chih‐Ying Chen, Ya‐Hui Lin, Wan‐Chi Pan, Chun‐Yi Liang, Hsiu‐Ching Liu, Lo‐Jei Ching, Pei‐Yu Weng, Min‐Ren Chiang, Ru‐Siou Hsu, Tsu‐Chin Chou, I‐Chi Lee, Lun‐De Liao, Li‐An Chu, Shih‐Hwa Chiou, Shang‐Hsiu Hu   +15 more
wiley   +1 more source

The <i>OsNAC25</i> Transcription Factor Enhances Drought Tolerance in Rice. [PDF]

Int J Mol Sci
Yang A, Luo Q, Liu L, Jiang M, Zhao F, Li Y, Liu B.   +6 more
europepmc   +1 more source

PRMT3‐Mediated H4R3me2a Promotes Primary Age‐Related Tauopathy by Driving Tau Hyperphosphorylation in Neuron

Advanced Science, EarlyView.
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu, Xinnan Liu, Fengyuan Tian, Yashuang Chen, Jingying Li, Xue Wang, Wenying Qiu, Xia Wang, Chao Ma, Wei Ge   +9 more
wiley   +1 more source

Decoding Mycoplasma Nucleases: Biological Functions and Pathogenesis. [PDF]

Toxins (Basel)
Yi X, Huang Y, Li X, Xu H, Liu C, Li C, Zeng Q, Luo H, Ye Z, He J, You X.   +10 more
europepmc   +1 more source

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

Advanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz, Dan Pascal Jean Albers, Fabian Zech, Julie Vandeput, Lieve Naesens, Giorgio Fois, Veronika Neubauer, Nico Preising, Emilia Schmierer, Yasser Almeida‐Hernandez, Moritz Petersen, Ludger Ständker, Sebastian Wiese, Peter Braubach, Manfred Frick, Eberhard Barth, Daniel Sauter, Frank Kirchhoff, Elsa Sanchez‐Garcia, Annelies Stevaert, Jan Münch   +24 more
wiley   +1 more source

Molecular insights into de novo small-molecule recognition by an intron RNA structure. [PDF]

Proc Natl Acad Sci U S A
Liu T, Xu L, Chung K, Sisto LJ, Hwang J, Zhang C, Van Zandt MC, Pyle AM.   +7 more
europepmc   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

Advanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu, Guixiang Zhou, Congzhi Zhang, Lin Chen, Donghao Ma, Lijun Zhang, Chunhua Jia, Ling Ma, Jiabao Zhang   +8 more
wiley   +1 more source

SequenceCraft: machine learning-based resource for exploratory analysis of RNA-cleaving deoxyribozymes. [PDF]

BMC Bioinformatics
Eremeyeva M, Din Y, Shirokii N, Serov N.
europepmc   +1 more source

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

Aggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai, Mengdie Li, Jinfa Ye, Mingyou Zhang, Jingbin Zhuang, Yuhang Cheng, Hongjin Li, Lang Ke, Xingyuan Wei, Yun Han, Huanhuan Liu, Gang Liu, Chengchao Chu   +12 more
wiley   +1 more source

Genome-Wide Identification and Functional Analysis of the Norcoclaurine Synthase Gene Family in <i>Aristolochia contorta</i>. [PDF]

Int J Mol Sci
Xu Y, Zhang S, Meng F, Liang W, Peng Y, Zhu B, Niu L, Wang C, Li C, Lu S.   +9 more
europepmc   +1 more source