Results 51 to 60 of about 126,025 (162)

Diagnostic value of DNA or RNA-based metagenomic next-generation sequencing in lower respiratory tract infections

open access: yesHeliyon
Objectives: We aimed to evaluate and compare the diagnostic performance of RNA-mNGS and DNA-mNGS workflow in bacterial pneumonia, fungal pneumonia and tuberculosis.
Jiafu Song   +4 more
doaj   +1 more source

Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From Aspergillus fumigatus: Reduced Fungal Virulence in a Mouse Infection Model

open access: yesFrontiers in Microbiology, 2020
The filamentous fungal pathogen Aspergillus fumigatus is one of the most common causal agents of invasive fungal infection in humans; the infection is associated with an alarmingly high mortality rate.
Azusa Takahashi-Nakaguchi   +14 more
doaj   +1 more source

Identification of a Novel Hypovirulence-Inducing Hypovirus From Alternaria alternata

open access: yesFrontiers in Microbiology, 2019
Mycoviruses are wide spread throughout almost all groups of fungi but only a small number of mycoviruses can attenuate the growth and virulence of their fungal hosts.
Huan Li   +8 more
doaj   +1 more source

Method for RNA extraction and transcriptomic analysis of single fungal spores

open access: yesMethodsX, 2020
Transcriptomic analysis of single cells has been increasingly in demand in recent years, thanks to technological and methodological advances as well as growing recognition of the importance of individuals in biological systems. However, the majority of these studies have been performed in mammalian cells, due to their ease of lysis and high RNA content.
Ivey A. Geoghegan   +3 more
openaire   +3 more sources

Hiding in plain sight: New virus genomes discovered via a systematic analysis of fungal public transcriptomes.

open access: yesPLoS ONE, 2019
The distribution and diversity of RNA viruses in fungi is incompletely understood due to the often cryptic nature of mycoviral infections and the focused study of primarily pathogenic and/or economically important fungi. As most viruses that are known to
Kerrigan B Gilbert   +3 more
doaj   +1 more source

Small RNAs: A new paradigm in fungal-fungal interactions used for biocontrol

open access: yesFungal Biology Reviews
In many eukaryotes, small RNAs (sRNAs) can mediate gene expression regulation through a mechanism known as RNA silencing. In fungi, RNA silencing plays a crucial role in numerous biological processes, including parasitic and mutualistic fungus-plant interactions.
Edoardo Piombo   +5 more
openaire   +2 more sources

Potential Roles of Fungal Extracellular Vesicles during Infection

open access: yesmSphere, 2016
Extracellular vesicles (EVs) are produced by virtually all cell types. Within the past few years, work in this field has revealed more information about fungal EVs. Fungal EVs have been shown to carry proteins, lipids, pigments, polysaccharides, and RNA;
Luna S. Joffe   +3 more
doaj   +1 more source

Inside-Out: From Endosomes to Extracellular Vesicles in Fungal RNA Transport

open access: yesFungal Biology Reviews, 2019
Membrane-coupled RNA transport is an emerging theme in fungal biology. This review focuses on the RNA cargo and mechanistic details of transport via two inter-related sets of organelles: endosomes and extracellular vesicles for intra- and intercellular RNA transfer.
Seomun Kwon   +4 more
openaire   +2 more sources

Effects on Friend Disease of Double-stranded RNA of Fungal Origin

open access: yesJournal of General Virology, 1971
Summary This paper reports the effects of treatment with double-stranded RNA of Friend disease, a virus-induced murine leukaemia. The salient feature of the disease is a progressive increase in spleen size; death normally results from rupture of the spleen.
D J, Pilch, D N, Planterose
openaire   +2 more sources

A Critical Role for CLSP2 in the Modulation of Antifungal Immune Response in Mosquitoes.

open access: yesPLoS Pathogens, 2015
Entomopathogenic fungi represent a promising class of bio-insecticides for mosquito control. Thus, detailed knowledge of the molecular mechanisms governing anti-fungal immune response in mosquitoes is essential.
Yan-Hong Wang   +6 more
doaj   +1 more source

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