Results 261 to 270 of about 1,540,463 (333)

A Comprehensive Evaluation of Analytical Method Parameters Critical to the Reliable Assessment of Therapeutic mRNA Integrity by Capillary Gel Electrophoresis. [PDF]

Electrophoresis
Tran JP, Gao J, Lansdell C, Lorbetskie B, Johnston MJW, Wang L, Li X, Lu H.   +7 more
europepmc   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

Advanced Genetics, EarlyView.
Optogenetics provides up to millisecond scale, cell type‐specific control of biology using light‐sensitive proteins. This review chronicles two decades of tool development, from microbial rhodopsins and photoactivated enzymes to allosteric switches, surveys broad applications in neuroscience, molecular and cell biology, cardiology, immunology, and ...
Xiao Duan, Mo Zhu, Shiqiang Gao
wiley   +1 more source

RVINN: a flexible modeling for inferring dynamic transcriptional and post-transcriptional regulation using physics-informed neural networks. [PDF]

Bioinformatics
Muto O, Guo Z, Yamaguchi R.
europepmc   +1 more source

Fat mass and obesity-associated protein downregulation trigger the activation of the sirtuin 1/forkhead box O1 signaling pathway, drive glycolysis, and promote the progression of renal cell carcinoma.

Cytojournal
Zhang Z, Zhang J, Zhang R.
europepmc   +1 more source

Methyltransferase 3-mediated m6A modification of Switch/sucrose non-fermenting-related matrix-associated actin-dependent regulator of chromatin subfamily a member 5 promotes mycobacterium tuberculosis-infected macrophage M1 polarization and inflammation.

Cytojournal
Chen C, Huang H.
europepmc   +1 more source

Laminar fluid ejection device enables high yield and preservation of mRNA and SaRNA LNP formulations. [PDF]

Sci Rep
Ho CH, Casmil IC, Sharma M, Rees T, Enright K, Allan N, Blakney AK.   +6 more
europepmc   +1 more source

Transcriptome sequencing showed the differential expression of circRNAs in human pulmonary microvascular endothelial cells in acute respiratory distress syndrome. [PDF]

J Thorac Dis
Wang N, Gao Y, Xue P, Surani S, Schwartz GS, Ma R, Li Y, Liu W.   +7 more
europepmc   +1 more source

rRNA loss induced by rifampicin addition in Escherichia coli reflects extraction artifacts rather than in vivo degradation. [PDF]

Sci Rep
Burck M, Nouaille S, Carpousis AJ, Cocaign-Bousquet M, Girbal L.   +4 more
europepmc   +1 more source

The efficacy and accuracy of ribosomal RNA depletion methods

Ahmed M, Bishop C, Betancourt A, Hunt V, Viney M.   +4 more
europepmc   +1 more source