Results 221 to 230 of about 203,757 (346)

Metagenomic and ribosomal transcript profiles of diabetic foot osteomyelitis in Hispanic patients: underestimated bacteria in biofilm persistence. [PDF]

open access: yesFront Cell Infect Microbiol
Díaz-Velis L   +8 more
europepmc   +1 more source

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis   +9 more
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi   +1 more
wiley   +1 more source

The Interplay of Dispersion and Thermal Shock in Pseudomonas Aeruginosa Biofilms

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Pathological bacterial biofilms formed on medical implants pose a significant challenge in clinical settings due to their resistance to antibiotics and the host immune response. Eradication of these biofilms by thermal shock has gained increasing attention as a means of eliminating these infections.
Hossein Zare, Josiah Power, Eric Nuxoll
wiley   +1 more source

A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria.

open access: yesJournal of Microbiological Methods, 2007
S. Chakravorty   +4 more
semanticscholar   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu   +4 more
wiley   +1 more source

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