Results 141 to 150 of about 44,420 (259)

A curated database of rumen ciliate protozoal 18S rRNA gene sequences for metataxonomic applications. [PDF]

BMC Genom Data
Lawther K, Tapio I, Vera-Ponce de León A, Aho VTE, Huws SA, Dimonaco NJ.   +5 more
europepmc   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

Angewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood, Sathishkumar Kurusamy, Mark Berney, C. Mark Smales, Elizabeth M. Topp, Joanna F. McGouran, Steven Ferguson   +6 more
wiley   +2 more sources

Structural evidence that RNA contributes to polymorphism of tau amyloid fibrils. [PDF]

iScience
Abskharon R, Jiang YX, Sawaya MR, Ge P, Zhang J, Boyer DR, Dolinsky JL, Pi J, Cascio D, Guo F, Eisenberg DS.   +10 more
europepmc   +1 more source

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

Advanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi, Valentina Lacconi, Arianna Mencattini, Micol Massimiani, Dolores Lobresca, Gaia Posanzini, Alessia Riccardi, Paola Casti, Michele D’Orazio, Gianni Antonelli, Giorgia Curci, Luisa Campagnolo, Eugenio Martinelli   +12 more
wiley   +1 more source

Ribosomal RNA processing undergoes surveillance by the mRNA guard protein Npl3. [PDF]

Cell Mol Life Sci
Lindemann AS, Yu F, Duan Y, Coban I, Schneider UM, Lamping JP, Khreiss A, Bohnsack KE, Krebber H.   +8 more
europepmc   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Development of a multiplex polymerase chain reaction assay for the detection of Piroplasma (<i>Babesia</i> spp. and <i>Theileria</i> spp.), <i>Anaplasma</i> spp., and <i>Trypanosoma evansi</i> in cattle. [PDF]

Open Vet J
Methawiroon J, Chalermwong P, Boonjint O, Chiawvitkan P, Wichianchot S, Thabthimsri C, Thongpoo P, Kamyingkird K, Jittapalapong S, Suwan E.   +9 more
europepmc   +1 more source

Standardized RNA extraction protocol for <i>Entamoeba</i> species: advancing molecular diagnostics and amebiasis control. [PDF]

Front Cell Infect Microbiol
Cox G, Melo M, Andrade A, Müller B, Dos Santos A, Moreira ADS, de Araujo NS, Moreira D, Parente T, Degrave W, Toma H, Waghabi M.   +11 more
europepmc   +1 more source

Automated eDNA sampling for marine monitoring and biosecurity: optimising temporal resolution, remote deployments, and community engagement. [PDF]

PeerJ
Scriver M, von Ammon U, Te Tai S, Tipene M, Watene K, Bamford N, Thomas AC, Zaiko A.   +7 more
europepmc   +1 more source