Results 241 to 250 of about 77,694 (290)

scRiskCell: A single‐cell framework for quantifying islet risk cells and their adaptive dynamics in type 2 diabetes

iMeta, EarlyView.
scRiskCell is an interpretable intelligent computational framework that leverages nearly 500,000 islet cell expression profiles from 106 donors across different continuous disease states. By calculating the intrinsic relationship between donor disease states and cell expression profiles, it assigns a pseudo‐cell state index to each cell.
Xueqin Xie, Changchun Wu, Fuying Dao, Kejun Deng, Dan Yan, Jian Huang, Hao Lyu, Hao Lin   +7 more
wiley   +1 more source

Exploring the protective role of caffeine against Taraxacum-Induced ribotoxic stress mediated through autophagy and mitochondrial depolarization. [PDF]

Sci Rep
Lin CJ, Liu ST, Wu ZS, Huang SM, Chen TW.   +4 more
europepmc   +1 more source

PMAT2: An efficient graphical assembly toolkit for comprehensive organellar genomes

iMeta, EarlyView.
We developed PMAT2, an advanced toolkit for lineage‐specific de novo assembly of plant, animal, and fungal mitochondrial genomes, as well as plant chloroplast genome. PMAT2 leverages optimized graph‐based strategies tailored to organelle genome complexity, enabling complete and accurate assemblies, even with approximately 1 × highly accurate PacBio ...
Fuchuan Han, Changwei Bi, Yicun Chen, Xiaogang Dai, Zefu Wang, Huaitong Wu, Ning Sun, Yanshu Qu, Yang Yang, Yangdong Wang, Tongming Yin   +10 more
wiley   +1 more source

Identifying Sarcocystis spp. infection in goats: a combined morphological, serological, and molecular approach. [PDF]

Parasitol Res
Steffen KD, Gos ML, Helman E, Unzaga JM, Arias RO, Moré G.   +5 more
europepmc   +1 more source

Participation of Deoxyribonucleic Acid Polymerase a in Amplification of Ribosomal Deoxyribonucleic Acid in Xenopus laevis [PDF]

, 1981
Zimmermann, Wolfgang
core  

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

Interdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang, Yufei Yang, Bingxu Chen, Yanmeng Zhao, Haitao Sun   +4 more
wiley   +1 more source

One Health implications and first evidence of environmental contamination of helminths in soil from goat farms in Ratchaburi, Thailand. [PDF]

Parasitol Res
Chan AHE, Pakdee W, Kaenkaew C, Sungpradit S, Charoennitiwat V, Kusolsuk T, Thaenkham U.   +6 more
europepmc   +1 more source

Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf, Elizabeth M. George, Jess Dong, Kimberly A. Rosvall   +3 more
wiley   +1 more source

An Update on the Morphology and Phylogeny of the Nanoplanktonic Dinoflagellate Prorocentrum nux. [PDF]

J Eukaryot Microbiol
Mordret S, MacKinnon J, Breglia SA, Slamovits CH, Chénard C.   +4 more
europepmc   +1 more source

Calcium butyrate efficacy in pediatric irritable bowel syndrome: Randomized placebo‐controlled multiomics‐based clinical trial

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and treatment involves nonpharmacological and pharmacological therapies, even if there is no optimal therapy. This randomized, placebo‐controlled, double‐blind trial aimed to evaluate the efficacy of calcium butyrate supplementation in ...
Fernanda Cristofori, Francesco Maria Calabrese, Ilaria Iacobellis, Monica Santamaria, Giuseppe Celano, Ilario Ferrocino, Emanuela Di Sabato, Rocco Pergola, Vanessa N. Dargenio, Leonardo Paulucci, Maria De Angelis, Ruggiero Francavilla   +11 more
wiley   +1 more source