From Bioinformatic Modeling to Clinical Observation: Potential Implications of Ribosomal RNA Folding in <i>Blastocystis</i> sp. Isolates from Symptomatic and Asymptomatic Carriers. [PDF]
Martínez-Hernández F +8 more
europepmc +1 more source
ABSTRACT Background Cutaneous T‐cell lymphoma (CTCL) is a rare and heterogeneous group of skin‐homing lymphomas with a largely unknown pathogenesis. Staphylococcus aureus (S. aureus) colonization has been implicated in exacerbating CTCL, particularly in advanced stages. Objectives This study assessed the prevalence of S.
Ida Lind Holm +9 more
wiley +1 more source
An optimized translating ribosome affinity purification protocol for low-abundance <i>Drosophila</i> tissues. [PDF]
Miller-Fleming L, Au WH, Whitworth AJ.
europepmc +1 more source
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li +4 more
wiley +1 more source
Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators. [PDF]
Muñoz López M +4 more
europepmc +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
pr2-Wormifier: A Bioinformatics Pipeline to Create Custom Reference Databases for Improved Metabarcoding of Marine Protists. [PDF]
Knell S, Romahn J, Bálint M.
europepmc +1 more source
Abstract Assigning taxonomic identity and thus assessing taxonomic diversity in gelatinous zooplankton is challenging due to their fragility and difficult preservation. Formalin fixation compromises DNA integrity, while flash‐freezing, ethanol, and acetone preservation affect morphological features. In this study, we developed a methodological protocol
Claudia Traboni +4 more
wiley +1 more source
The use of Benzonase to produce ribosome footprints simplifies translational levels quantification by Ribo-seq. [PDF]
Eastman G, Bloom GS, Sotelo-Silveira JR.
europepmc +1 more source

