Results 141 to 150 of about 436,504 (250)
Advanced Materials Technologies, EarlyView.We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
G/C-ending and synonymous codon bias define functional translational programs that shape human tissue and cancer proteomes. [PDF]
NAR Genom BioinformRashad S, Niizuma K.
europepmc +1 more source
Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices
Advanced Materials Technologies, EarlyView.Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen +11 more
wiley +1 more source
The EP424R protein of African swine fever virus functions as a 2'-O-methyltransferase and plays an important role in viral replication. [PDF]
mBioWang Z +8 more
europepmc +1 more source
Advanced Science, EarlyView.We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Post-Transcriptional Regulatory Mechanism Based on CsrA and <i>rpoS</i> in Extremophile Sulfur Oxidizer <i>Acidithiobacillus caldus</i>. [PDF]
MicroorganismsZhu Y, Chen P, Yang H, Tong Y, Feng S.
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Universal paralogs provide a window into evolution before the last universal common ancestor. [PDF]
Cell GenomGoldman AD, Fournier GP, Kaçar B.
europepmc +1 more source
ELABELA Targets Mitochondria to Modulate Heart Development
Advanced Science, EarlyView.The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source