Results 221 to 230 of about 5,035,452 (301)

RNA-Polymer Conjugates via Direct Incorporation of the Chain Transfer Agent and PET-RAFT Polymerization. [PDF]

Biomacromolecules
Hu X, Jeong J, Murata H, Yin R, Das SR, Matyjaszewski K.   +5 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

CRISPR/Cas13a-mediated interfacial cleaving of hairpin RNA reporter for PEAK1 nucleic acid sensing. [PDF]

RSC Adv
Zhuang X, Duan Z, Ge X, Wang Y, Gao Y, Liu J, Zhou S, Zeng C, Cui F, Zhou Q.   +9 more
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Mechanistic insights into direct DNA and RNA strand transfer and dynamic protein exchange of SSB and RPA. [PDF]

Nucleic Acids Res
Paul T, Lee IR, Pangeni S, Rashid F, Yang O, Antony E, Berger JM, Myong S, Ha T.   +8 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Unraveling the mitochondrial genome of <i>Quercus litseoides</i>: a step towards conservation of an endangered species. [PDF]

Front Plant Sci
Shen RH, Li Y, Yang LH, Zheng SS, Yan X, Kozlowski G, Dai XL, Song YG.   +7 more
europepmc   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

FEBS Open Bio, 2014
Kenji Takahashi, I. Yan, T. Kogure, Hiroaki Haga, T. Patel   +4 more
semanticscholar   +1 more source

Protocol for mouse brain tissue processing and downstream analysis of circRNA-protein interactions in vivo. [PDF]

STAR Protoc
Sztachera M, Wendlandt-Stanek W, Piwecka M.   +2 more
europepmc   +1 more source