High-throughput Screening of Sequence Elements Associated with RNA Localization. [PDF]
Zeng X +6 more
europepmc +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
CircPRKCA Promotes NSCLC Progression via miR-200b-3p/FRMD6/SNAI2 Axis. [PDF]
Zhong H +5 more
europepmc +1 more source
Cross‐Level Regulatory Interactions Underlying Human Immune Aging
We performed multi‐omics sequencing on peripheral blood samples from 69 individuals aged 23–75 years and identified multi‐layered molecular interaction networks underlying the process of immune senescence, which provides a comprehensive multi‐omics framework for understanding immune aging and identifying potential strategies to delay immunosenescence ...
Quanyou Wu +9 more
wiley +1 more source
Genome-wide identification of m<sup>6</sup>A methyltransferase genes and m<sup>6</sup>A modification participates in the response to cold stress in rice. [PDF]
He S +9 more
europepmc +1 more source
Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley +1 more source
Correction: Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis. [PDF]
Wang JY +9 more
europepmc +1 more source
Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus +5 more
wiley +1 more source
Comprehensive mapping of the 5' and 3' untranslated regions of <i>Aspergillus fumigatus</i> reveals diverse mechanisms of mRNA processing including premature transcription termination. [PDF]
Schrettenbrunner L +4 more
europepmc +1 more source
Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero +1 more
wiley +1 more source

