Results 261 to 270 of about 1,113,600 (301)
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RNA Editing with Viral RNA-Dependent RNA Polymerase
ACS Synthetic Biology, 2022RNA editing is currently attracting attention as a method for editing genetic information without injury to the genome. The most common approach to edit RNA sequences involves the induction of an A-to-I change by adenosine deaminase acting on RNA (ADAR). However, this method only allows point editing.
Shinzi Ogasawara, Ai Yamada
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Viral sensing by RNA helicases
Virologie, 2020A key aspect of antiviral immunity is the distinction between "self" and "non-self" components. This distinction can be established through the detection of double-stranded RNA (dsRNA), a common sign of viral infection, by cytosolic RNA helicases.
Claire, Rousseau, Carine, Meignin
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Critical Reviews in Biochemistry, 1988
Recent progress in molecular biological techniques revealed that genomes of animal viruses are complex in structure, for example, with respect to the chemical nature (DNA or RNA), strandedness (double or single), genetic sense (positive or negative), circularity (circle or linear), and so on.
A, Ishihama, K, Nagata
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Recent progress in molecular biological techniques revealed that genomes of animal viruses are complex in structure, for example, with respect to the chemical nature (DNA or RNA), strandedness (double or single), genetic sense (positive or negative), circularity (circle or linear), and so on.
A, Ishihama, K, Nagata
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Virology, 1974
Abstract Influenza viral messenger RNA (mRNA) free from both ribosomal RNA and newly synthesized host mRNA was isolated from the polyribosomes of infected canine kidney cells. Cordycepin was added to infected cells to inhibit ribosomal RNA and host mRNA synthesis.
P R, Etkind, R M, Krug
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Abstract Influenza viral messenger RNA (mRNA) free from both ribosomal RNA and newly synthesized host mRNA was isolated from the polyribosomes of infected canine kidney cells. Cordycepin was added to infected cells to inhibit ribosomal RNA and host mRNA synthesis.
P R, Etkind, R M, Krug
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Relationship between viral RNA and viral protein synthesis
Virology, 1962Abstract Low concentrations of p-fluorophenylalanine (5–10 μg/ml) inhibit the maturation of Western equine encephalomyelitis and poliomyelitis viruses. Much higher concentrations are required (125 μg/ml) to inhibit the synthesis of the respective infectious RNA. By means of fluorescent antibodies against poliovirus, it was found that the formation of
E, WECKER, K, HUMMELER, O, GOETZ
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Nature Chemical Biology, 2005
Retroviruses have a stretch of RNA that dimerizes during viral particle formation. A new study suggests that RNA flexibility in the monomeric form may facilitate dimerization or other RNA-dependent viral functions.
Valerie Calabro, Alan D Frankel
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Retroviruses have a stretch of RNA that dimerizes during viral particle formation. A new study suggests that RNA flexibility in the monomeric form may facilitate dimerization or other RNA-dependent viral functions.
Valerie Calabro, Alan D Frankel
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Viral suppressors of RNA silencing
Current Opinion in Biotechnology, 2001The suppression of RNA silencing by plant viruses represents a viral adaptation to a novel host antiviral defense. Three types of viral suppressors have been identified through the use of a variety of silencing suppression assays. The first two types of suppressor are capable of a complete or partial reversal of pre-existing RNA silencing; the third ...
W X, Li, S W, Ding
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1969
Publisher Summary The pace of research on RNA virus replication and the huge amount of related literature that has accumulated in the past 6 years attest to the wide interest in the topic. There has also been some controversy and apparent confusion, probably largely because of pressure for publication priority. In this chapter, methods for detecting,
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Publisher Summary The pace of research on RNA virus replication and the huge amount of related literature that has accumulated in the past 6 years attest to the wide interest in the topic. There has also been some controversy and apparent confusion, probably largely because of pressure for publication priority. In this chapter, methods for detecting,
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Viral suppressors of RNA silencing
Trends in Plant Science, 2011The infection and replication of viruses in the host induce diverse mechanisms for combating viral infection. One of the best-studied antiviral defence mechanisms is based on RNA silencing. Consistently, several viral suppressors of RNA silencing (VSRs) have been identified from almost all plant virus genera, which are surprisingly diverse within and ...
József, Burgyán, Zoltán, Havelda
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Viral vector-mediated RNA interference
Current Opinion in Pharmacology, 2010RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to revolutionize medical interventions. Delivery of inhibitory RNAs to target tissues needs to be safe, efficient, and for many diseases, long-lasting, in order to exploit this endogenous mechanism for therapeutic purposes.
Linda B, Couto, Katherine A, High
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