Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung+6 more
wiley +1 more source
Novel sofosbuvir derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective. [PDF]
Alrehaily A+4 more
europepmc +1 more source
Amentoflavone from Selaginella tamariscina inhibits SARS-CoV-2 RNA-dependent RNA polymerase
The SARS-CoV-2 pandemic caused millions of deaths due to its prominent infectivity and mortality. Although the vaccines and medicines for SARS-CoV-2 are on the market, new coronavirus variants like influenza are expected to reemerge continuously ...
Kyoung Won Youn+7 more
doaj
Studies on nuclear RNA polymerases and the role of cyclic nucleotides on transcription [PDF]
1. An assay for measuring the endogenous RNA polymerase activity in Tetrahymena pyriformis nuclei was developed. The reaction rate was linear for 60 minutes at 25°C. This rate of the reaction was dependent on the presence of four nucleoside triphosphates
Nadjati, Amira
core
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang+8 more
wiley +1 more source
A fungal RNA-dependent RNA polymerase is a novel player in plant infection and cross-kingdom RNA interference. [PDF]
Cheng AP+8 more
europepmc +1 more source
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis+5 more
wiley +1 more source
Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase. [PDF]
Yao YL+17 more
europepmc +1 more source
DNA- and RNA-Dependent DNA Polymerases: Progressive Changes in Rabbit Endometrium During Preimplantation Stage of Pregnancy1 [PDF]
Wen-Kuang Yang+2 more
openalex +1 more source