Results 231 to 240 of about 582,722 (350)

Integrating Iso-seq and RNA-seq data for the reannotation of the killifish telencephalon transcriptome. [PDF]

Sci Data
Ayana R, Krutikhina T, Van Houcke J, Zandecki C, Mariën V, Maes GE, Seuntjens E, Arckens L.   +7 more
europepmc   +1 more source

Simultaneous Isoform Discovery and Quantification from RNA-Seq

, 2012
D. Hiller, Wing Hung Wong
openalex   +1 more source

RNA-Seq transcriptome profiling of mouse oocytes after in vitro maturation and/or vitrification [PDF]

, 2017
Lei Gao, Gongxue Jia, Ai Li, Haojia Ma, Zhengyuan Huang, Shien Zhu, Yunpeng Hou, Xiangwei Fu   +7 more
openalex   +1 more source

Epigenetic Targeting of Senescent Cells Prevents the Deleterious Effects of Obstructive Sleep Apnea on Growing Skeleton

Advanced Science, EarlyView.
Chronic intermittent hypoxia induces premature senescence of osteoprogenitor cells in long bone metaphysis via HIF1α‐mediated EZH2‐H3k27me3 downregulation, leading to impaired bone growth. Restoration of H3K27me3 level via UTX inhibition rescues osteogenesis and growth impairment in young mice.
Xiaonan Liu, Peilin Zhang, Zhongyi Su, Yong Feng, Zhenger Zhou, Sa Pang, Yicheng Wang, Jiacheng Hu   +7 more
wiley   +1 more source

Single-cell metabolome and RNA-seq multiplexing on single plant cells. [PDF]

Proc Natl Acad Sci U S A
Kang M, Vu AH, Casper AL, Kim R, Wurlitzer J, Heinicke S, Yeroslaviz A, Caputi L, O'Connor SE.   +8 more
europepmc   +1 more source

scater:pre-processing, quality control, normalisation and visualisation of single-cell RNA-seq data in R [PDF]

, 2016
Davis J. McCarthy, Kieran R. Campbell, Aaron T. L. Lun, Quin F. Wills   +3 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Conformal inference for reliable single cell RNA-seq annotation. [PDF]

Bioinformatics
López-De-Castro M, García-Galindo A, González-Gomariz J, Armañanzas R.   +3 more
europepmc   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Bulk RNA-seq deconvolution heterogeneity across paired pancreatic cancer human samples. [PDF]

Front Genet
Jansen RJ, Munro SA, Antwi SO, Rabe KG, Sicotte H.   +4 more
europepmc   +1 more source