Results 191 to 200 of about 2,497,031 (299)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Nonequilibrium mechanism of transcription termination from observations of single RNA polymerase molecules

, 1999
Hong Yin, Irina Artsimovitch, Robert Landick, Jeff Gelles   +3 more
openalex   +2 more sources

Equal Amounts of Intracellular and Virion‐Enclosed Hepatitis C Virus RNA Are Associated with Peripheral‐Blood Mononuclear Cells In Vivo [PDF]

, 2006
Philipp Kaiser, Barbara Niederöst, Béda Joos, Viktor von Wyl, Milos Opravil, Rainer Weber, Huldrych F. Günthard, Marek Fischer   +7 more
openalex   +1 more source

Characterization of RNA Editing in Oxidative and Glycolytic Skeletal Muscles of Yak. [PDF]

Biology (Basel)
Shi Y, Wu X, Liang C, Guo X, Ma X, Yan P, Chu M, Wu X.   +7 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

CisBP-RNA: a web resource for eukaryotic RNA-binding proteins and their motifs. [PDF]

Nucleic Acids Res
Rosado-Tristani DA, Albu M, Chen X, Sasse A, Laverty KU, Ray D, Tam CL, Ernst K, Lawson LP, Morris QD, Hughes TR, Weirauch MT.   +11 more
europepmc   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization [PDF]

, 2016
María Llanos Valero, Rosario Sabariegos, Francisco J. Cimas, Celia Perales, Esteban Domingo, Ricardo Sánchez‐Prieto, Antonio Más   +6 more
openalex   +1 more source

ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites. [PDF]

Proc Natl Acad Sci U S A
Rosenwasser Z, Cohen-Fultheim R, Levitt M, Levanon EY, Oren G.   +4 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source