Results 191 to 200 of about 5,194,805 (386)

Seapration of B. subtilis DNA into complementary strands. II. Template functions and composition as determined by transcription with RNA polymerase. [PDF]

, 1968
J D Karkas, Rivka Rudner, Erwin Chargaff
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Effect of Hydrocortisone on Hela Cells with Special Reference to the RNA Metabolism

, 1969
Hideo Suzuki, Motoyasu Ohsawa, Hiroyoshi Endo   +2 more
openalex   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Tumor-Educated Platelet RNA and Circulating Free RNA: Emerging Liquid Biopsy Markers for Different Tumor Types

Frontiers in Bioscience-Landmark
The incidence and mortality from malignant tumors continue to rise each year. Consequently, early diagnosis and intervention are vital for improving patient’ prognosis and survival.
Haiyang Hu, Huangqin Song, Bin Han, Haoliang Zhao, Jiefeng He   +4 more
doaj   +1 more source

The role of DNA in RNA synthesis, IX. Nucleoside triphosphate termini in RNA polymerase products.

, 1965
Umadas Maitra, H Hurwitz
openalex   +1 more source

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Nature Protocols, 2012
C. Trapnell, Adam Roberts, L. Goff, G. Pertea, Daehwan Kim, David R. Kelley, Harold Pimentel, S. Salzberg, J. Rinn, L. Pachter   +9 more
semanticscholar   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

RNA-RNA, DNA-DNA, and DNA-RNA Polymorphism

Biophysical Journal, 1986
Struther Arnott, Rick P. Millane, H.-S. Park, Rengaswami Chandrasekaran   +3 more
openaire   +3 more sources

REPLICATION OF VIRAL RNA, VI. NUCLEOTIDE COMPOSITION OF THE REPLICATIVE FORM OF TOBACCO MOSAIC VIRUS RNA AND OF ITS COMPONENT STRANDS [PDF]

, 1965
Charles Weissmann, Martin Billeter, Morton C. Schneider, C.A. Knight, Severo Ochoa   +4 more
openalex   +1 more source