Results 201 to 210 of about 3,741,253 (359)

CHARACTERISTICS AND COMPOSITION OF RNA CODING UNITS [PDF]

, 1962
Johannes Matthaei, Oliver W. Jones, Robert G. Martin, Marshall W. Nirenberg   +3 more
openalex   +1 more source

Mapping RNA–RNA interactions [PDF]

Nature Methods, 2020
openaire   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

RiboFlow: Conditional De Novo RNA Sequence-Structure Co-Design via Synergistic Flow Matching [PDF]

arXiv
Ribonucleic acid (RNA) binds to molecules to achieve specific biological functions. While generative models are advancing biomolecule design, existing methods for designing RNA that target specific ligands face limitations in capturing RNA's conformational flexibility, ensuring structural validity, and overcoming data scarcity.
arxiv  

Studies on homopolymer synthesis with irradiated DNA in the RNA polymerase system

, 1967
Hans Kröger, L. Schuchmann, Eiko E. Petersen, U. Hagen   +3 more
openalex   +2 more sources

POLIOVIRUS-INDUCED RNA POLYMERASE AND THE EFFECTS OF VIRUS-SPECIFIC INHIBITORS ON ITS PRODUCTION [PDF]

, 1963
David Baltimore, Hans J. Eggers, Richard M. Franklin, Igor Tamm   +3 more
openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

ON THE RNA SYNTHESIZED DURING THE LAMPBRUSH PHASE OF AMPHIBIAN OÖGENESIS [PDF]

, 1964
Eric H. Davidson, V. G. Allfrey, A. E. Mirsky   +2 more
openalex   +1 more source

RNA-RNA, DNA-DNA, and DNA-RNA Polymorphism

Biophysical Journal, 1986
Struther Arnott, Rick P. Millane, H.-S. Park, Rengaswami Chandrasekaran   +3 more
openaire   +3 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source