Results 211 to 220 of about 2,455,342 (249)

The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation. [PDF]

PLoS Biol
Deng X, Xie S, Zhou M, Yuan Q, Wu S, Huang P, Chen M, Zeng J, Guo P, Qin J, Chen C, Liu J, Liu B, He X, Sun L, Zhang H, Li L, Pan T.   +17 more
europepmc   +1 more source

核磁気緩和による核酸,Transfer RNA[phe],の研究

, 1977
文和 林
openalex   +1 more source

Long Noncoding RNA Lnc-MTPAP-1 Overexpressed by Particulate Matter Suppresses Apoptosis in Non-Small Cell Lung Cancer (NSCLC) Cells [PDF]

Ji Won Park, Daeun Kang, Minhyeok Lee, Yong J. Lee, Su Yel Lee, Sin Yung Woo, Keum Jin Yang, In Beom Jeong, Hee Sun Park, Ji Woong Son, Sun Jung Kwon   +10 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Liquid-Liquid Phase Separation: Mechanisms, Roles, and Implications in Cellular Function and Disease. [PDF]

FASEB Bioadv
Thakur DK, Padole S, Sarkar T, Arumugam S, Chattopadhyay S.   +4 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Heterogeneity in responses to ribosome-targeting antibiotics mediated by bacterial RNA repair. [PDF]

Nat Commun
Hindley HJ, Gong Z, Moradian S, Giuliano MG, Sapelkin A, Kotta-Loizou I, Buck M, Engl C, Weiße AY.   +8 more
europepmc   +1 more source

Circular RNA FCHO2 promotes airway remodeling in COPD via regulating nuclear translocation of PTBP1 to repress the splicing of GRN pre-mRNA [PDF]

Yanfei Liu, Yucong Wang, Y. Fei, Hu Xu, Cheng Xue, Li Liudong, Lei Huang, Pengcheng Liu, Renming Li, Ge Shan, Liang Chen, Dahai Zhao   +11 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Characterization of HIV-1 Particles Co-Purified With Three Extracellular Vesicle Subtypes From the Raji CD4 DCIR Cell Line, a Hybrid Model of CD4 T Cells and Dendritic Cells. [PDF]

J Extracell Biol
Boucher J, Rousseau A, Gilbert C.
europepmc   +1 more source